New Combo Drug Jentadueto XR Approved for Diabetes

Roni Shye
Roni Shye, PharmD BCGP BCACP, is a licensed pharmacist in the states of Florida, Ohio, and Pennsylvania.
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Jentadueto XR (metformin/linagliptin) is the newest once-daily combination drug approved by the FDA to treat type 2 diabetes.

Combination drugs can also be a convenient way to join together two drugs that work differently to treat a particular health condition, and extended release versions like Jentadueto XR mean you only need to take your prescription once per day. In addition, many medications are combined because they work better together than either medication alone.

Do your own research though—while combinations can be easier to take, they can also be pricier than taking the active ingredients as separate medications.

What is Jentadueto XR?
Jentadueto XR is an extended-release once-daily combination of metformin and the active ingredient in Tradjenta, linagliptin.

What are the advantages to using Jentadueto XR?

Convenience, for one. One pill, once per day, for two medications is much simpler than scheduling multiple doses for more than one prescription.

The all-in-one dose form also means you’re more likely to take your medication as prescribed—which means you’re more likely to keep your diabetes under control.

What are the disadvantages?

Potentially, cost. Jentadueto XR hasn’t hit pharmacies yet, but the immediate release version, Jentadueto, costs about $375 per month using a discount.

However, if you are already taking Tradjenta and extended-release metformin separately, Jentadueto XR may still be a good option for you—since Tradjenta is still brand-only, the cost is about the same.

How will Jentadueto XR be available?
Jentadueto XR will be a tablet in / and / strengths.

How is Jentadueto XR taken?
Jentadueto XR is taken once daily with food. It should be swallowed whole—don’t split, dissolve, cut, or chew the tablets.

What are the side effects of Jentadueto XR?

The most common side effects associated with Jentadueto XR include stuffy nose, runny nose, sore throat, and diarrhea.

When will Jentadueto XR be available?

At the moment, there isn’t an expected availability date for Jentadueto XR—but watch for it in pharmacies in the upcoming months.

Want more information?

See the press announcement from the manufacturer here.

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