First, let’s talk about what makes Glynase and Diabeta similar. Both of these medications are used in type 2 diabetes to improve glycemic control and lower blood sugar levels, both are 2nd generation drugs in the sulfonylurea class and work by telling the pancreas to release more insulin, and both have a form of glyburide as the active ingredient.
So, how does Glynase differ from Diabeta?
Glynase is micronized glyburide which has a different duration of action, absorption, and dosage than its nonmicronized counterpart, Diabeta or Micronase (regular glyburide). Micronized glyburide contains smaller particles that allow the medication to be absorbed better by the body—therefore, lower doses can be used.
How are these medications taken?
What if you have a SULFA allergy?
A reaction is possible with any of the sulfonylureas, however, remember, glyburide is a 2nd generation sulfonylurea. Reactions occur more frequently with the 1st generation sulfonylurea, chlorpropamide (Diabinese).
Can these medications be substituted for one another?