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Betibeglogene Autotemcel
BETIBEGLOGENE AUTOTEMCEL treats beta thalassemia. It works by helping your body make healthy red blood cells, which reduces the need for blood transfusions. Compare gene therapy drugs.
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Biologic Drug: Biologic drugs are made from living cells and are often expensive. Because biologic drugs are difficult to copy, they typically don’t have generic alternatives available. Learn More.

Betibeglogene Autotemcel Side Effects

What should I watch for?

Visit your care team for regular health checks while on this medication. It is important for you to have regular check-ups and blood work done for at least 15 years after this treatment.

Talk to your care team about your risk of cancer. You may be more at risk for certain types of cancer if you take this medication.

If you need an HIV test, talk to your care team about which test to use. This medication may cause a false-positive result if certain tests are used.

Do not donate blood, organs, tissues, or cells any time after receiving this treatment.

Talk to your care team if you may be pregnant. You will need a negative pregnancy test before starting this medication. Contraception is recommended while taking this medication and for at least 6 months after your last dose. Your care team can help you find the option that works for you.

Talk to your care team before breastfeeding. Changes to your treatment plan may be needed.

If your partner can get pregnant, use a condom during sex while taking this medication and for at least 6 months after the last dose.

The conditioning medication may cause infertility. Talk to your care team if you are concerned about your fertility.

What are the side effects?

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Bleeding—bloody or black, tar-like stools, vomiting blood or brown material that looks like coffee grounds, red or dark brown urine, small red or purple spots on skin, unusual bruising or bleeding
  • Infection—fever, chills, cough, or sore throat

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

What may interact with this drug?

  • Granulocyte-colony stimulating factor
  • Iron chelator medications
  • Live virus vaccines