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Belzutifan

BELZUTIFAN treats kidney cancer. It may also be used to treat some types of cancer and tumors in people with von Hippel-Lindau syndrome. It works by blocking a protein that causes cancer cells to grow and multiply. This helps to slow or stop the spread of cancer cells. Compare HIF-2a inhibitors.

Prescription Settings

Specialty Drug: Specialty drugs are often expensive and may need to be filled through specialty pharmacies. Learn More

What is Belzutifan?

What should I tell my doctor?

They need to know if you have any of these conditions:

Low red blood cell levels
An unusual or allergic reaction to belzutifan, other medications, foods, dyes, or preservatives
If you or your partner are pregnant or trying to get pregnant
Breastfeeding

How should I use this drug?

Take this medication by mouth. Take it as directed on the prescription label at the same time every day. Do not cut, crush, or chew this medication. Swallow the tablets whole. You can take it with or without food. If it upsets your stomach, take it with food. Your care team may change your dose or tell you to stop taking this medication if you get side effects. Do not change your dose or stop taking it unless your care team tells you to.

Each bottle contains tablets and a drying packet (desiccant) to keep the tablets dry. Do not eat the drying packet.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your care team about the use of this medication in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

If you vomit after taking your dose, do not take another dose. Take your next dose at your usual time the next day.

Where should I store this drug?

Keep out of the reach of children and pets.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Get rid of any unused medication after the expiration date.

To get rid of medications that are no longer needed or have expired:

Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
If you cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put it in the trash, empty the medication out of the container. Mix the medication with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.