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Belimumab
Specialty Drug

Benlysta

BELIMUMAB is a medicine used to treat a certain type of systemic lupus erythematosus (SLE). This medicine is used with standard therapy for SLE. It is not a cure. Compare BLyS-specific inhibitors.
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Belimumab Side Effects

What should I watch for?

Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.

Your condition will be monitored carefully while you are receiving this medicine.

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Common and Rare Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

Bleeding, blistering, burning, coldness, skin discoloration, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site

body aches or pain

chest congestion

chills

cough

diarrhea

difficulty with breathing or swallowing

dizziness

ear congestion

fever

headache

hives

itching, pain, redness, swelling, tenderness, or warmth of the skin

joint pain

loss of appetite

lower back or side pain

muscle aches and pains

nausea or vomiting

pain or tenderness around the eyes and cheekbones

swelling of the eyes, face, or inside of the nose

shortness of breath or trouble breathing

sneezing

sore throat

stuffy or runny nose

sweating

tightness in the chest

unusual tiredness or weakness

Less common

Black, tarry stools

bloody or cloudy urine

depression

difficult, burning, or painful urination

fast heartbeat

frequent urge to urinate

hoarseness

sores, ulcers, or white spots on the lips or in the mouth

swollen glands

tender, swollen glands in the neck

unusual bleeding or bruising

voice changes

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Arm or leg pain

headache, severe and throbbing

unable to sleep

Less common

Abdominal or stomach pain

weakness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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