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Sulfamethoxazole / Trimethoprim Coupon - Sulfamethoxazole / Trimethoprim 800mg/160mg tablet
Bactrim, SeptraSulfamethoxazole / Trimethoprim
SULFAMETHOXAZOLE; TRIMETHOPRIM or SMX-TMP is a combination of a sulfonamide antibiotic and a second antibiotic, trimethoprim. It is used to treat or prevent certain kinds of bacterial infections. It will not work for colds, flu, or other viral infections. The lowest GoodRx price for the most common version of sulfamethoxazole / trimethoprim is around $6.28, 63% off the average retail price of $17.29. Compare antifolate / sulfa antibiotic combinations.
Prescription Settings
sulfamethoxazole / trimethoprim(generic)
20 tablets
Sulfamethoxazole / Trimethoprim Coupon - Sulfamethoxazole / Trimethoprim 800mg/160mg tablet
sulfamethoxazole / trimethoprim(generic)
20 tablets

Bactrim Side Effects

What should I watch for?

Tell your doctor or health care professional if your symptoms do not improve. Drink several glasses of water a day to reduce the risk of kidney problems.

Do not treat diarrhea with over the counter products. Contact your doctor if you have diarrhea that lasts more than 2 days or if it is severe and watery.

This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use a sunscreen. Do not use sun lamps or tanning beds/booths.


Common and Rare Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:


Abdominal or stomach pain

black, tarry stools

blistering, peeling, or loosening of the skin

changes in skin color

chest pain


cough or hoarseness

dark urine



fever with or without chills

general feeling of tiredness or weakness



joint or muscle pain

light-colored stools

loss of appetite

lower back or side pain


pain, tenderness, or swelling of the foot or leg

painful or difficult urination

pale skin


red skin lesions, often with a purple center

red, irritated eyes

shortness of breath

sore throat

sores, ulcers, or white spots in the mouth or on the lips

swollen or painful glands

tightness in the chest

unpleasant breath odor

unusual bleeding or bruising

vomiting of blood


yellow eyes or skin

Incidence not known

Abdominal or stomach tenderness

back, leg, or stomach pains

bleeding gums

blindness or vision changes

blisters, hives, or itching


blood in the urine or stools

bluish-colored lips, fingernails, or palms

burning, crawling, itching, numbness, painful, prickling, "pins and needles", or tingling feelings

burning of the face or mouth

chest pain

cloudy urine



continuing ringing or buzzing or other unexplained noise in the ears


cracks in the skin

decreased frequency or amount of urine

diarrhea, watery and severe, which may also be bloody

difficulty with breathing

difficulty with swallowing

fainting spells

general body swelling

general feeling of discomfort or illness

hair loss

hearing loss


increased thirst


irregular heartbeat

large, flat, blue, or purplish patches in the skin

large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

loss of heat from the body

muscle or joint pain


not able to pass urine

numbness or tingling in the hands, feet, or lips

pain or burning while urinating

pinpoint red spots on the skin

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

raised red swellings on the skin, the buttocks, legs, or ankles

redness of the white part of the eyes

redness, swelling, or soreness of the tongue

sores, ulcers, or white spots on the lips or in the mouth

soreness of the muscles

stiff neck or back

swelling of the face, hands, legs, and feet

unsteadiness, trembling, or other problems with muscle control or coordination

unusual weight loss

weakness in the hands or feet

weakness or heaviness of the legs

weight gain

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Passing of gas

Incidence not known


feeling of constant movement of self or surroundings

feeling sad or empty

increased sensitivity of the skin to sunlight


lack of feeling or emotion

loss of interest or pleasure


redness or other discoloration of the skin

seeing, hearing, or feeling things that are not there

sensation of spinning

severe sunburn

trouble concentrating

trouble sleeping


weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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GoodRx is not sponsored by or affiliated with any of the pharmacies identified in its price comparisons. All trademarks, brands, logos and copyright images are property of their respective owners and rights holders and are used solely to represent the products of these rights holders. This information is for informational purposes only and is not meant to be a substitute for professional medical advice, diagnosis or treatment. GoodRx is not offering advice, recommending or endorsing any specific prescription drug, pharmacy or other information on the site. GoodRx provides no warranty for any of the pricing data or other information. Please seek medical advice before starting, changing or terminating any medical treatment.
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