Prescription Prices and Coupons from GoodRx
Type your drug name (like Atorvastatin, Sildenafil, etc)
Astagraf XL Coupon - Astagraf XL 1mg capsule
Astagraf XL
TACROLIMUS is used to decrease the immune system's response to a transplanted kidney. Compare CNI immunosuppressants.
Prescription Settings
30 capsules
Astagraf XL Coupon - Astagraf XL 1mg capsule
Astagraf XL(brand)
30 capsules

Astagraf XL Side Effects

What should I watch for?

Visit your doctor or health care professional for regular checks on your progress. You will need frequent blood checks.

If you get a cold or other infection while receiving this medicine, call your doctor or health care professional. Do not treat yourself. The medicine may decrease your body's ability to fight infections.

Talk to your doctor about your risk of cancer. You may be more at risk for certain types of cancers if you take this medicine.

This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.


Common and Rare Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Abnormal dreams








frequent urination

general feeling of discomfort or illness


itching, skin rash

joint pain

loss of appetite

loss of energy or weakness

mental depression

muscle aches and pains

muscle trembling or twitching


pale skin

runny nose

seeing or hearing things that are not there



skin rash

sore throat

stomach pain

swelling of the feet or lower legs


trembling and shaking of the hands

trouble sleeping

unusual bleeding or bruising

unusual tiredness or weakness


Less common

Blurred vision

chest pain

increased sensitivity to pain

muscle cramps

numbness or pain in the legs

ringing in the ears



Enlarged heart

flushing of the face or neck

weight loss

Incidence not known

Black, tarry stools

blistering, peeling, loosening of the skin


bloody urine




fast, slow, or irregular heartbeat


increased thirst


joint pain


lower back or side pain

pinpoint red spots on the skin

pounding or rapid pulse

red skin lesions, often with a purple center

red, irritated eyes

skin sores

ulcers or white spots in the mouth or on the lips


weight gain

yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common


difficulty with moving

lack or loss of strength

muscle stiffness

Less common

Body aches or pain

burning or stinging of the skin

cracks in the skin




excessive muscle tone

false beliefs that cannot be changed by facts

false or unusual sense of well-being

feeling of constant movement of self or surroundings

feeling that others are watching you or controlling your behavior

feeling that others can hear your thoughts

increased sensitivity of the skin to sunlight

large, flat, blue or purplish patches in the skin

muscle tension or tightness

painful blisters on the trunk of the body

painful cold sores or blisters on the lips, nose, eyes, or genitals


poor insight and judgment

problems with memory or speech

quick to react or overreact emotionally

rapidly changing moods

redness or other discoloration of the skin


scaly skin

sensation of spinning

severe mood or mental changes

severe sunburn

sleepiness or unusual drowsiness

sore mouth or tongue

sores on the skin

swelling or inflammation of the mouth

tender, swollen glands in the neck

trouble recognizing objects

trouble thinking and planning

trouble walking

unusual behavior

white patches in the mouth, tongue, or throat

Incidence not known

Change in color vision

decreased weight

difficulty seeing at night

feeling hot and cold

hearing loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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