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Artemether and LumefantrineCoartem
ARTEMETHER; LUMEFANTRINE is an antimalarial agent. It is used to treat malaria infections. Compare antimalarials.
Prescription Settings
24 tablets
24 tablets

Artemether and Lumefantrine Side Effects

What should I watch for?

Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse. Tell your doctor if you get flu-like symptoms (chills, fever, muscle pains, or headaches) again after you have finished all of your medicine.

Birth control pills may not work properly while you are taking this medicine. Talk to your doctor about using an extra method of birth control.

Tell you doctor or healthcare professional if you vomited any of your doses or if you are not able to eat.


Common and Rare Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Abdominal or stomach pain



fast, irregular, pounding, or racing heartbeat or pulse



muscle aches

pale skin

right upper abdominal or stomach pain and fullness

sore throat

stuffy or runny nose

troubled breathing with exertion

unusual bleeding or bruising

unusual tiredness or weakness

Less common

Accumulation of pus

acid or sour stomach


black, tarry stools

bladder pain

blood in the urine

bloody or cloudy urine

body aches or pain

change in hearing

chest pain

cloudy urine


cough producing mucus

decreased urine


difficult, burning, or painful urination

difficulty with breathing

difficulty with swallowing


dry mouth

ear congestion

ear drainage

earache or pain in the ear

frequent urge to urinate

general feeling of discomfort or illness


increased thirst


joint pain

loss of appetite

loss of voice

lower back or side pain

mood changes

muscle pain or cramps

nasal congestion

nausea or vomiting

noisy breathing

numbness or tingling in the hands, feet, or lips

red rash with watery, yellow-colored, or pus filled blisters


shortness of breath


sores, ulcers, or white spots on the lips or in the mouth

stomach discomfort, upset, or pain


swollen glands

swollen, red, tender area of infection

thick yellow to honey-colored crusts

tightness in the chest

troubled with sleeping

Incidence not known

Large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Difficulty with moving

lack or loss of strength

muscle aching or cramping

muscle pain or stiffness


unable to sleep

weight loss

Less common

Back pain

burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

burning, dry, or itching eyes

continuing ringing or buzzing or other unexplained noise in the ears

difficulty having a bowel movement (stool)

discharge or excessive tearing

dizziness or lightheadedness

feeling of constant movement of self or surroundings

hearing loss

hives or welts

redness of the skin

redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid

sensation of spinning

shakiness and unsteady walk

shakiness in the legs, arms, hands, or feet

trembling or shaking of the hands or feet

uncontrolled eye movements

unsteadiness, trembling, or other problems with muscle control or coordination

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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