What’s the Deal With Zetia (Ezetimibe): A Good Alternative to Statins for Preventing Heart Attack and Stroke?
Dr. Sharon Orrange - November 25, 2014
When I read criticisms of doctors prescribing expensive medications that might not benefit patients at all, I think of Zetia (ezetimibe) as the poster child. News came out last week after the IMPROVE-IT trial that seemed to pump it up, but what we learned from this large trial may surprise you and let you down at the same time.
Dr. Sharon Orrange - November 19, 2013
Guidelines change the way we practice medicine. This is a good thing because sweeping guidelines are based on interpretations of years of good strong studies. The new cholesterol guidelines place the burden of lowering LDL cholesterol on statin drugs because they work.
Lowering LDL cholesterol is now not just about chasing a number (70, 100, 130) but about lowering yours by 25-50% if you meet the indications for treatment. See More
Dr. Sharon Orrange - November 15, 2013
For the first time in a decade, the American College of Cardiology (ACC) and the American Heart Association (AHA) have made new recommendations for who we treat with statins for high cholesterol and toward what goal. The new guidelines are different. Here is what you need to know:
• Gone are the recommended LDL cholesterol targets, specifically those that ask physicians to treat patients with cardiovascular disease to less than 100 or the optional goal of less than 70. See More
Dr. Sharon Orrange - June 14, 2013
Liptruzet is a new player in the cholesterol lowering game making an appearance as the second combination of Zetia (ezetimibe) and a statin drug—in this case, atorvastatin (Lipitor). Liptruzet is the combination of the active ingredient of Zetia called ezetimibe (not a statin) mixed with the well known statin atorvastatin, and will be used to lower LDL cholesterol. Vytorin, a combination of ezetimibe and simvastatin, was released in 2004. See More
Dr. Sharon Orrange - January 30, 2013
Aside from Zetia there haven’t been any good non-statin options for lowering LDL Cholesterol. Statin drugs like Lipitor (atorvastatin), Zocor (simvastatin) and Crestor work well to lower the “bad” cholesterol, the LDL, and have remained first line therapy for many years. Finally, there may be something new to get excited about. But, it does have some “issues.”
Dr. Sharon Orrange - January 20, 2012
Almost one in four Americans now take a statin, so many of you may have questions about a new or existing prescription. Here are the answers to the most common questions I am asked about statin drugs by my patients:
- Will they hurt my liver? Out of the ordinary liver tests are only seen in fewer than 1 in 100 patients taking statin drugs, and this will go away if you stop the medication. See More