ALPHA-1-PROTEINASE INHIBITOR (AL fa - 1 - PROH tee neys in HIB i ter) is a drug that is used to replace an enzyme in patients with lung problems caused by low levels of alpha1 antitrypsin. It is not a cure. Compare human alpha-1 proteinase inhibitors.

Zemaira Side Effects

What should I watch for?

Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse. Your condition will be monitored carefully while you are receiving this medicine.

This medicine can cause serious allergic reactions. Ask your doctor or health care professional about an epinephrine pen and/or other supportive care for certain severe allergic reactions.

This medicine is made from human plasma, and there is a small risk that it may contain certain types of viruses or bacteria. All products are processed to kill most viruses and bacteria. If you have questions concerning the risk of infections, discuss them with your doctor or health care professional.


Interactions with Medications

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

Bladder pain

bloody or cloudy urine

body aches or pain



difficult, burning, or painful urination

difficulty with breathing

ear congestion


frequent urge to urinate


loss of voice

lower back or side pain

nasal congestion

runny nose


sore throat

unusual tiredness or weakness


Bloating or swelling of the face, arms, hands, lower legs, or feet

blurred vision

chest pain

cough producing mucus


difficult or labored breathing


feeling faint, dizzy, or lightheadedness

flushing or redness of the skin, especially on the face and neck

general feeling of discomfort or illness

joint pain

loss of appetite

muscle aches and pains



noisy breathing

pounding in the ears

rapid weight gain


slow or fast heartbeat


tightness in the chest

tingling of the hands or feet

trouble sleeping

unusual weight gain or loss


Incidence not known


difficulty with swallowing

dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

fast, pounding, or irregular heartbeat or pulse


itching, puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

skin rash

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Feeling of warmth

itching skin

muscle or bone pain

pain or tenderness around the eyes and cheekbones

redness of the face, neck, arms, and occasionally, upper chest

sudden sweating


Back pain


change in taste

changes in vision


hives or welts

loss of taste


redness of the skin

sleepiness or unusual drowsiness

swelling of the joints

unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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