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Tolvaptan
Specialty Drug

Samsca

TOLVAPTAN is used to treat low levels of sodium in the blood. Compare vaptans.
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Tolvaptan Side Effects

What should I watch for?

Your condition will be monitored carefully while you are receiving this medicine.

To prevent dehydration, have water available to drink at all times while taking this medicine. Drink when you are thirsty, unless your doctor or healthcare professional tells you otherwise.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.

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Interactions with Medications

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Abdominal or stomach pain

blurred vision

dry mouth

flushed, dry skin

frequent urination

fruit-like breath odor

increased hunger

increased thirst

increased urination

increased volume of pale, dilute urine

nausea

sweating

thirst

troubled breathing

unexplained weight loss

unusual tiredness or weakness

vomiting

Less common

Abdominal or stomach tenderness

anxiety

blood in the urine

bloody stools

blue lips, fingernails, or skin

bruising

chest pain

confusion

cough

coughing or vomiting blood

dark-colored urine

dizziness or lightheadedness

fainting

fast, slow, irregular or shallow heartbeat

fever

irregular, fast or slow, or shallow breathing

loss of consciousness

muscle cramps or spasms

muscle pain or stiffness

pain, redness, or swelling in the arm or leg

persistent bleeding or oozing from puncture sites, mouth, or nose

pink or red urine

rash

rectal bleeding

shortness of breath

sudden shortness of breath or troubled breathing

sweating

vaginal bleeding

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Difficulty having a bowel movement (stool)

lack or loss of strength

Less common

Loss of appetite

weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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