TENECTEPLASE is used to dissolve blood clots that form in certain blood vessels. This medicine is used when a blood clot in a heart artery causes a heart attack. Compare anticoagulants.

Tnkase Side Effects

What should I watch for?

You will be closely monitored to check your progress after you receive this medicine. Follow the advice of your doctor or health care professional exactly. You may need bed rest to minimize the risk of bleeding.

This medicine can make you bleed more easily. This effect can last for several days. Try to avoid damage to your teeth and gums when you brush or floss your teeth, and to avoid any other injury to yourself.

Do not take aspirin, ibuprofen, or other nonprescription pain relievers during or for several days after this medicine unless otherwise instructed by your doctor or health care professional.


Interactions with Medications

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Bleeding or bruising of any kind, especially around the place of injection

collection of blood under skin

Less common or rare

Abdominal or stomach pain or swelling

back pain or backaches

blood in throat

blood in urine

bloody or black, tarry stools



coughing up blood

difficulty swallowing


fast, slow or irregular breathing

fast, slow or irregular heartbeat




shortness of breath and/or wheezing

skin rash, hives or itching

swelling of eyes, face, lips, or tongue

tightness in chest

unusual tiredness or weakness

vomiting of blood or material that looks like coffee grounds


Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Bloody nose

unexplained nosebleeds

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