What should I watch for?
Visit your doctor or health care professional for regular checks on your progress. Side effects to this medicine occur most frequently during the first 3 months of therapy. To make sure you do not develop any problems, you will need to have blood tests before you start this medicine and then every 2 weeks for the first 3 months.
Notify your doctor or health care professional and seek emergency treatment if you develop breathing problems; changes in vision; chest pain; severe, sudden headache; pain, swelling, warmth in the leg; trouble speaking; sudden numbness or weakness of the face, arm, or leg. These can be signs that your condition has gotten worse.
This medicine can cause serious blood problems. This can mean risk of infection or bleeding. Avoid activities that increase your risk of bleeding. Tell your doctor or health care professional at once if have any unusual bleeding or bruise easily or an infection that will not get better.
If you are going to have surgery or dental work, tell your doctor or health care professional that you are taking this medicine.
Interactions with Medications
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Less common or rare
Abdominal or stomach pain (severe) or swelling
blistering, peeling, or loosening of the skin or lips or mucous membranes (moist lining of many body cavities, including the mouth, lips, inside of nose, anus, and vagina)
blood in eyes
bloody or black tarry stools
bruising or purple areas on skin
change in mental status
coughing up blood
dark or bloody urine
headache (severe or continuing)
joint pain or swelling
pale color of skin
paralysis or problems with coordination
pinpoint red spots on skin
red lesions on the skin, often with a purple center
red, thickened, or scaly skin
sores, ulcers, or white spots in mouth
stammering or other difficulty in speaking
unusually heavy or unexpected menstrual bleeding
vomiting of blood or material that looks like coffee grounds
yellow eyes or skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.