Ticagrelor Coupon - Ticagrelor 90mg tablet


Ticagrelor (Brilinta) is an expensive drug used to prevent heart attack, stroke, or other vascular events in people who have had a recent heart attack or who have severe chest pain. This drug is slightly more popular than comparable drugs. There are currently no generic alternatives to Brilinta. It is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower. Compare antiplatelet drugs.
Ticagrelor Coupon - Ticagrelor 90mg tablet

What is Ticagrelor?

Commonly Used Brand Name(s)Brilinta

Therapeutic ClassificationsPlatelet Aggregation Inhibitor

Pharmacologic ClassificationsADP-Induced Aggregation Inhibitor



Blackbox WarningTOP

Oral route (Tablet)

Ticagrelor, can cause significant, sometimes fatal, bleeding. Do not use in patients with active pathological bleeding or history of intracranial hemorrhage. Do not start in patients undergoing urgent CABG. If possible, manage bleeding without discontinuing ticagrelor. Stopping ticagrelor increases the risk of subsequent cardiovascular events. Maintenance doses of aspirin above 100 mg reduce the effectiveness of ticagrelor and should be avoided .


Ticagrelor is used alone or together with aspirin to lessen the chance of heart attack, stroke, or other serious problems with your heart or blood vessels. It is given to patients who have already had a heart attack or severe chest pain, stroke, or to people with other blood circulation problems that could lead to a stroke or heart attack.

A heart attack or stroke may occur when a blood vessel in the heart or brain is blocked by a blood clot. Ticagrelor reduces the chance that a harmful blood clot will form by preventing certain cells in the blood from clumping together. This effect of ticagrelor may also increase the chance of serious bleeding in some people.

This medicine is available only with your doctor's prescription.

Proper UseTOP

Take this medicine exactly as directed by your doctor. Ticagrelor will not work properly if you take less of it than directed. Taking more ticagrelor than directed may increase the chance of serious side effects without increasing the helpful effects.

This medicine comes with a Medication Guide. It is very important that you read and understand this information. Be sure to ask your doctor about anything you do not understand.

You may take this medicine with or without food.

If you are unable to swallow the tablets whole:

  • You may crush and mix the tablets in a glass of water and swallow it right away.
  • Refill the glass with more water, stir, and swallow the mixture again.
  • This mixture may also be given through a nasogastric tube. Flush the tube with more water to rinse all of the medicine into the stomach.

If you are using this medicine for a condition called acute coronary syndrome, your doctor may tell you to take aspirin while you are using ticagrelor. In this case, do not change the dose or stop taking the aspirin without talking to your doctor first.


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage form (tablets):
    • For prevention of blood clots after unstable angina (chest pain), non-ST-elevation myocardial infarction (a type of heart attack), or ST-elevation myocardial infarction or STEMI:
      • Adults—At first, 180 milligrams (mg) or 2 tablets taken as a single dose. Then, 90 mg two times a day. Your doctor may also give you a loading dose of aspirin 325 mg once a day, then 75 to 100 mg once a day to be taken together with this medicine.
      • Children—Use and dose must be determined by your doctor.

Missed DoseTOP

If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Use & StorageTOP

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Before UsingTOP

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Appropriate studies have not been performed on the relationship of age to the effects of ticagrelor in the pediatric population. Safety and efficacy have not been established.


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of ticagrelor in the elderly.


Pregnancy CategoryExplanation
All TrimestersCAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast FeedingTOP

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug InteractionsTOP

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Other InteractionsTOP

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

  • Grapefruit Juice

Other Medical ProblemsTOP

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Bleeding, pathological and active (eg, from peptic ulcers or head injury) or
  • Intracranial hemorrhage (bleeding in the head), history of or
  • Liver disease, severe—Should not be used in patients with these conditions.
  • Bleeding problems, history of or
  • Lung disease or breathing problems (eg, asthma or COPD)—Use with caution. May make these conditions worse.
  • Liver disease, moderate—Use with caution. You doctor may adjust your dose.


It is very important that your doctor check your progress at regular visits. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it. Blood tests may be needed to check for unwanted effects.

Tell all medical doctors, dentists, nurses, and pharmacists you go to that you are taking this medicine. Ticagrelor may increase the risk of serious bleeding during a surgery, other medical procedures (eg, coronary stent procedure), or some kinds of dental work. You may need to stop using this medicine at least 5 days before a surgery, medical procedure, or dental work.

Do not change your dose or stop taking this medicine without checking first with your doctor. To do so may increase the chance of having a heart attack, blood clotting problems, or other serious conditions.

While you are using this medicine, if you have any kind of bleeding, it may take longer than usual to stop, especially if you hurt yourself. Stay away from rough sports or other situations where you could be bruised, cut, or injured. Be careful when using sharp objects, including razors and fingernail clippers.

This medicine may increase your chance of bleeding or bruising. Check with your doctor right away if you notice any unusual bleeding or bruising, black, tarry stools, blood in the urine or stools, or pinpoint red spots on your skin. Avoid picking your nose. If you need to blow your nose, blow it gently.

If you have unexpected or unexplained shortness of breath, difficult or labored breathing, or tightness in the chest, tell your doctor right away.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

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