Specialty Drug
FENTANYL is a pain reliever. It is used to treat breakthrough cancer pain that your long acting pain medicine does not control. Do not use this medicine for a pain that will go away in a few days like pain from surgery, doctor or dentist visits. The medicine is used only by people who have been taking an opioid or narcotic pain medicine for at least a week. Compare opioids.

Insurance Coverage: Many major insurance plans no longer cover Subsys as of 2015. Learn More


Subsys Latest News

Get the latest updates on this drug from the GoodRx medical team

FDA Requires New Warning on Opioid Pain Medications

The GoodRx Pharmacist - June 15, 2016

The FDA has issued a new required warning for all opioid pain medications. If you are taking an opioid, you should be aware of a few potential side effects, including reactions with other medications, and effects on hormone levels.

What are some examples of opioid medications?

Opioids are powerful prescription-only medications, used to manage manage pain when other treatments may not work. Some common opiods include:

Why exactly was the FDA safety alert issued?

The FDA identified some safety concerns for anyone using opioid pain medications:

  • They can interact with many other medications
  • They can cause problems with a person’s adrenal glands
  • They can decrease sex hormone levels

What kind of medications can react with opioids?

Specifically, opioids may react with antidepressants and migraine medications. See More

40+ Brand-Name Drugs Dropped By Insurance in 2015

Elizabeth Davis - August 20, 2014

For many Americans with health insurance, more than 40 popular brand-name drugs may no longer be covered starting in January 2015. Express Scripts and Caremark, companies that handle pharmacy benefits for more than 200 million Americans, are removing over 40 drugs from their formularies at the end of 2014. This is in addition to the more than 50 drugs removed last year.

What are Express Scripts and Caremark?

Express Scripts and Caremark are companies that administer prescription drug benefits for many health insurance companies and Tricare. See More

Straight Out of Pulp Fiction: An Injection for Opioid Overdose You Can Use at Home

Dr. Sharon Orrange - April 09, 2014

Heroin, Oxycontin or any opioid overdose is easily reversed with naloxone. You’ve seen it in the movies and it’s true, naloxone works to wake people up from the dead, well . . . most of the time. Now people won’t have to wait for paramedics to arrive or to get to the ER, it will be available as a prescription.

The FDA has approved Evzio (naloxone injection) for the emergency treatment of known or suspected opioid overdose, which as you know manifests as respiratory and/or central nervous system depression. See More

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