Stagesic (hydrocodone / acetaminophen) was an opioid / acetaminophen combination used to treat moderate to severe pain, but has been discontinued because it contained more than 325 mg of acetaminophen per dose.

Stagesic Latest News

Get the latest updates on this drug from the GoodRx medical team

Is Your Medication Making You Tired?

Dr. Sharon Orrange - June 10, 2014

One in ten visits to a primary care doctor is for fatigue. While certainly not the only cause, your medications can be the culprit for making you sleepy. Here are the players you need to know about.

Beta blockers. These are medications used for high blood pressure, migraine prevention, control of heart rate in atrial fibrillation, and they improve mortality after heart attack. Ok, now for the downside. They can make you sleepy. See More

Which Medicine Is Best for Pain: Percocet, Vicodin, or Tylenol #3?

Dr. Sharon Orrange - April 16, 2014

You’ve had surgery, you have a toothache, or you can’t move without severe back pain and Tylenol (acetaminophen) and ibuprofen aren’t helping. What’s next?

Conventionally, patients who have moderate to severe pain have been offered one of the opioid-nonopioid combination drugs, such as acetaminophen plus hydrocodone or oxycodone.

Are they the same? What’s better? What is the prescription I have? It seems complicated but it’s not—let’s shed light on the common players:

Acetaminophen + Codeine:

You may have been prescribed Tylenol #3 or Tylenol #4 in the past. See More

Prescription Acetaminophen Dose Changes: What You Need to Know

The GoodRx Pharmacist - January 17, 2014

General Overview

What has been discontinued?

All prescription drug products with more than 325 mg of acetaminophen (also known as APAP or paracetamol, and the active ingredient in Tylenol). The FDA has asked that manufacturers limit the amount of acetaminophen in these products to 325 mg to prevent liver injury from overdose.

Some examples of these drugs include Vicodin (hydrocodone/acetaminophen), Percocet (oxycodone/acetaminophen), Fioricet (butalbital/acetaminophen/caffeine), and Fioricet with codeine (butalbital/acetaminophen/caffeine/codeine). See More

Acetaminophen: Curbing Overdose and Liver Toxicity

The GoodRx Pharmacist - October 11, 2013

Acetaminophen (Tylenol) toxicity has become more of an issue, especially due to the rise of combination products. These include prescription pain medications (such as hydrocodone/acetaminophen, oxycodone/acetaminophen, butalbital/acetaminophen, acetaminophen/codeine and tramadol/acetaminophen) in which acetaminophen is used as a second pain reliever. It is also widely available over the counter, and many over-the-counter combinations that advertise pain or fever relief contain acetaminophen as well. See More

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