Simvastatin is an HMG-CoA reductase inhibitor or "statin," which lowers levels of cholesterol and triglycerides in the blood. Statins may also reduce the risk of heart attack or stroke in patients with risk factors for heart disease. Simvastatin is also available as brand name Zocor. Juvisync, which combines Januvia (sitagliptin, a diabetes medication) with simvastatin, treats both diabetes and high cholesterol.
Get the latest updates on this drug from the GoodRx medical team.
by Dr. Sharon Orrange – October 01, 2015
The best treatment in diseases such as atherosclerosis, or coronary artery disease, is prevention. Lifestyle changes like exercise, quitting smoking and changing your diet are an important place to start, but sometimes you just need more help.
Drugs like the statin medications work well to lower cholesterol but may come with some side effects. I am often asked by patients: what natural remedies really work to lower cholesterol?
There are some options out there, but before I show you some promising and well-studied plants that may help lower cholesterol, please remember a few things: these are unregulated and may carry issues of toxicity. See More
by Dr. Sharon Orrange – July 23, 2015
Statins are among the most commonly prescribed drugs in the world for a reason: they can lower your LDL cholesterol (the “bad cholesterol”) by 20 – 60%. Statins are also helpful for the prevention of heart disease in some people with high cholesterol.
Time with your doctor can be limited, so you may not have heard all of the upsides and downsides when you were prescribed a statin. See More
by The GoodRx Pharmacist – May 29, 2015
When you hear the phrase “a rare but serious side effect,” what comes to mind? With so many pharmaceutical commercials on television these days you may be be used to hearing that phrase.
Statins like Lipitor (atorvastatin), Zocor (simvastatin), and Crestor (rosuvastatin), are some of the most popular cholesterol medications, and they come with this “fine print” phrase. Statins can cause a rare but serious side effect called rhabdomyolysis. See More
by Dr. Sharon Orrange – April 09, 2015
Two very different sets of guidelines exist for when to use cholesterol lowering medications in children transitioning into adulthood. Should those aged 17 – 21 with high cholesterol be on a cholesterol-lowering drug—a statin drug? How and when to treat those younger than 40, and especially those folks 17 – 21, is not nearly as well studied as in older folks, so guidelines are based on expert recommendations from limited data in this age group. See More
by The GoodRx Pharmacist – March 10, 2015
HMG-CoA reductase inhibitors—better known as statins—are a group of medications used to treat high cholesterol. High cholesterol, if not treated with proper lifestyle modifications and/or medications, can result in life-threatening cardiovascular events like heart attack or stroke.
Your total cholesterol is made up of both “good” and “bad” parts as well as some other miscellaneous parts. The “good” part of your cholesterol is known as HDL, and the “bad” part of your cholesterol is known as LDL. See More
by Dr. Sharon Orrange – January 27, 2015
Medications certainly aren’t the only thing that will cause hair loss, but they are often overlooked. If you feel like you are losing your hair, one of your first steps is to look at your medication list. You will also pay attention to other well known causes including poor diet (caloric or protein restriction), major illness or surgeries, major psychological stress, significant weight loss, chronic iron deficiency, thyroid disorders, and childbirth. See More
by Dr. Sharon Orrange – December 04, 2014
People are more likely to take their cholesterol medication when it costs less. While this may seem obvious to you, the medical community did a study on this question to find come to that conclusion! The results were published in the Annals of Internal Medicine, a medical journal, where they made news.
Generic medications are cheaper than brand names—so you are more likely to fill and take your statin cholesterol medication if it’s generic, and you will do better overall. See More
by Dr. Sharon Orrange – November 15, 2013
For the first time in a decade, the American College of Cardiology (ACC) and the American Heart Association (AHA) have made new recommendations for who we treat with statins for high cholesterol and toward what goal. The new guidelines are different. Here is what you need to know:
• Gone are the recommended LDL cholesterol targets, specifically those that ask physicians to treat patients with cardiovascular disease to less than 100 or the optional goal of less than 70. See More
by The GoodRx Pharmacist – May 15, 2013
If you take a statin like Lipitor (atorvastatin) or Zocor (simvastatin) to lower your cholesterol, you’ve probably been told to avoid grapefruit and grapefruit juice. You might be wondering—why? If so, here’s your answer.
Statins are metabolized in the liver by a select group of enzymes. Grapefruit can also attach to these enzymes, which can lead to decreased statin metabolism—meaning your body won’t process the medication the way it’s supposed to. See More
by Dr. Sharon Orrange – April 23, 2013
Lifelong treatment with a medication is a tall order for some people—so it isn’t all that surprising that discontinuation rates are high for some of the most popular cholesterol medications, the statin drugs.
Why is this a problem? If you’re on a drug to lower your cholesterol, you will need to keep taking your prescription or your cholesterol will go back up. Statins in particular can help lower cholesterol up to 60%, but their effects will go away a couple of months after you stop taking them. See More
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