Simvastatin is an HMG-CoA reductase inhibitor or 'statin,' which lowers levels of cholesterol and triglycerides in the blood. Statins may also reduce the risk of heart attack or stroke in patients with risk factors for heart disease. Simvastatin is also available as brand name Zocor. Juvisync, which combines Januvia (sitagliptin, a diabetes medication) with simvastatin, treats both diabetes and high cholesterol.
Get the latest updates on this drug from the GoodRx medical team.
by Dr. Sharon Orrange – April 09, 2015
Two very different sets of guidelines exist for when to use cholesterol lowering medications in children transitioning into adulthood. Should those aged 17 – 21 with high cholesterol be on a cholesterol-lowering drug—a statin drug? How and when to treat those younger than 40, and especially those folks 17 – 21, is not nearly as well studied as in older folks, so guidelines are based on expert recommendations from limited data in this age group. See More
by The GoodRx Pharmacist – March 10, 2015
HMG-CoA reductase inhibitors—better known as statins—are a group of medications used to treat high cholesterol. High cholesterol, if not treated with proper lifestyle modifications and/or medications, can result in life-threatening cardiovascular events like heart attack or stroke.
Your total cholesterol is made up of both “good” and “bad” parts as well as some other miscellaneous parts. The “good” part of your cholesterol is known as HDL, and the “bad” part of your cholesterol is known as LDL. See More
by Dr. Sharon Orrange – January 27, 2015
Medications certainly aren’t the only thing that will cause hair loss, but they are often overlooked. If you feel like you are losing your hair, one of your first steps is to look at your medication list. You will also pay attention to other well known causes including poor diet (caloric or protein restriction), major illness or surgeries, major psychological stress, significant weight loss, chronic iron deficiency, thyroid disorders, and childbirth. See More
by Dr. Sharon Orrange – December 04, 2014
People are more likely to take their cholesterol medication when it costs less. While this may seem obvious to you, the medical community had to study this question and publish results in the Annals of Internal Medicine where it made news. Generic medications are cheaper than brand names so not only are you more likely to take your cholesterol medication/statin if it’s generic, but you will do better overall. See More
by Dr. Sharon Orrange – November 15, 2013
For the first time in a decade, the American College of Cardiology (ACC) and the American Heart Association (AHA) have made new recommendations for who we treat with statins for high cholesterol and toward what goal. The new guidelines are different. Here is what you need to know:
• Gone are the recommended LDL cholesterol targets, specifically those that ask physicians to treat patients with cardiovascular disease to less than 100 or the optional goal of less than 70. See More
by The GoodRx Pharmacist – May 15, 2013
If you are taking a statin like Lipitor (atorvastatin) or Zocor (simvastatin) you probably have been told to avoid grapefruit and grapefruit juice. You might have asked yourself—why? If so, here is your answer.
Statins are metabolized in the liver by a select group of enzymes. Grapefruit can also attach to these enzymes, which can lead to decreased statin metabolism—meaning your body won’t process the medication the way it’s supposed to. See More
by Dr. Sharon Orrange – April 23, 2013
Lifelong treatment with a medication is a tall order for some people. So it is not surprising that discontinuation rates are high for the cholesterol medications, the “statin” drugs.
Despite their benefits, statin drugs are commonly discontinued. Serious side effects like rhabdomyolysis (breakdown of muscle fibers) and liver test abnormalities are very rare. Many patients know that statins have been reported to cause muscle pain, and because everyone has muscle pain or joint pain from time to time, blaming the medication is a natural tendency. See More
by Elizabeth Davis – March 28, 2013
When it comes to saving on your prescriptions, sometimes the way to get the best price isn’t as straightforward as simply using a coupon or switching to a generic.
Recently, I visited a doctor to try and figure out why I was having headaches. It took months, but eventually I was diagnosed with migraines; then, I had to work with my doctor to find the right medication to manage the migraines.
Like many Americans, I have health insurance, but even with insurance, the cost of my drugs was giving me a headache. See More
by Dr. Sharon Orrange – February 04, 2013
If you take prescription drugs to treat a chronic illness, it’s possible to save more than 50% off cost of your medication by simply splitting your pills.
Sadly, it’s not all that easy to know when pill splitting is all right.
Not all pills can be split. However, many doctors and insurance companies are advising this strategy with an increasing number of medicines. (It’s also worth noting that the American Medical Association, the American Pharmacists Association, and most pharmaceutical companies oppose pill-splitting. See More
by Dr. Sharon Orrange – January 30, 2013
Aside from Zetia there haven’t been any good non-statin options for lowering LDL Cholesterol. Statin drugs like Lipitor (atorvastatin), Zocor (simvastatin) and Crestor work well to lower the “bad” cholesterol, the LDL, and have remained first line therapy for many years. Finally, there may be something new to get excited about. But, it does have some “issues.”
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