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Sargramostim
Specialty Drug

Leukine

SARGRAMOSTIM, GM-CSF (sar GRAM oh stim) helps the body make more blood cells. It is used to increase the number of blood cells after chemotherapy or with a blood or bone marrow transplant. Compare leukocyte growth factors.
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Sargramostim Side Effects

What should I watch for?

Visit your doctor for regular check ups. You will need blood work done while you are taking this medicine.

This medicine may make you feel flushed, faint, dizzy, or weak on your first dose. Tell your doctor if your symptoms do not get better.

Do not become pregnant while taking this medicine. Talk to your doctor about birth control. Call your doctor right away if you think that you may be pregnant.

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Interactions with Medications

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Abdominal pain

black, tarry stools

bloating or swelling of face, arms, hands, lower legs, or feet

blood in eye

bloody nose

bloody stools

blurred vision

body aches or pain

bone pain

chest pain

cloudy urine

congestion

cough

decrease in urine output or decrease in urine-concentrating ability

difficult or labored breathing

drowsiness

dry mouth

dryness or soreness of throat

eye pain

fast, pounding, or irregular heartbeat or pulse

fatigue

fever

flushed, dry skin

fruit-like breath odor

hoarseness

increased hunger

increased thirst

increased urination

irregular heartbeat

large amount of cholesterol in the blood

loss of appetite

mood or mental changes

muscle spasms [tetany] or twitching seizures

nausea or vomiting

rapid weight gain

redness in whites of eyes

runny nose

shortness of breath

sweating

tender, swollen glands in neck

tightness in chest

tingling of hands or feet

trouble in swallowing

troubled breathing

trembling

unusual tiredness or weakness

unusual weight gain or loss

voice changes

vomiting of blood or material that looks like coffee grounds

wheezing

yellow eyes or skin

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

General feeling of discomfort or illness

headache

rash

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Chills

diarrhea

difficulty in moving

fear or nervousness

itching skin

lack or loss of strength

muscle pain or stiffness

pain in joints

sleeplessness

trouble sleeping

unable to sleep

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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