Roxicet Coupon - Roxicet 5mg/325mg tablet
FDA Update

Oxycodone / Acetaminophen

Oxycodone/acetaminophen (Roxicet, Endocet, Percocet) is a moderately priced drug used to treat moderate to severe pain.This drug is more popular than comparable drugs. It is available in multiple brand and generic versions. Generic oxycodone/acetaminophen is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower. Compare opioid / acetaminophen combinations.

Roxicet Side Effects

What should I watch for?

Tell your doctor or health care professional if your pain does not go away, if it gets worse, or if you have new or a different type of pain. You may develop tolerance to the medicine. Tolerance means that you will need a higher dose of the medication for pain relief. Tolerance is normal and is expected if you take this medicine for a long time.

Do not suddenly stop taking your medicine because you may develop a severe reaction. Your body becomes used to the medicine. This does NOT mean you are addicted. Addiction is a behavior related to getting and using a drug for a non-medical reason. If you have pain, you have a medical reason to take pain medicine. Your doctor will tell you how much medicine to take. If your doctor wants you to stop the medicine, the dose will be slowly lowered over time to avoid any side effects.

There are different types of narcotic medicines (opiates). If you take more than one type at the same time or if you are taking another medicine that also causes drowsiness, you may have more side effects. Give your health care provider a list of all medicines you use. Your doctor will tell you how much medicine to take. Do not take more medicine than directed. Call emergency for help if you have problems breathing or unusual sleepiness.

Do not take other medicines that contain acetaminophen with this medicine. Always read labels carefully. If you have questions, ask your doctor or pharmacist.

If you take too much acetaminophen get medical help right away. Too much acetaminophen can be very dangerous and cause liver damage. Even if you do not have symptoms, it is important to get help right away.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.

The medicine will cause constipation. Try to have a bowel movement at least every 2 to 3 days. If you do not have a bowel movement for 3 days, call your doctor or health care professional.

Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty or water may help. Contact your doctor if the problem does not go away or is severe.


Interactions with Medications

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Abdominal or stomach pain

black, tarry stools


dark urine





light-colored stools

loss of appetite



unpleasant breath odor

unusual tiredness or weakness

vomiting of blood

yellow eyes or skin


Cough or hoarseness

fever with or without chills

general feeling of tiredness or weakness

lower back or side pain

painful or difficult urination

sore throat

sores, ulcers, or white spots on the lips or in the mouth

unusual bleeding or bruising

Incidence not known

Back, leg, or stomach pains

bleeding gums


blood in the urine or stools

blue lips and fingernails

blurred vision

burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

chest pain or discomfort

clay-colored stools

cloudy urine




coughing that sometimes produces a pink frothy sputum

decreased awareness or responsiveness

decreased frequency or amount of urine

difficult or labored breathing

difficult or painful urination

difficult, fast, noisy breathing, sometimes with wheezing

difficulty in passing urine (dribbling)

difficulty with swallowing

dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position


dry mouth

extremely shallow or slow breathing


fast or deep breathing

fast, slow, irregular, pounding, or racing heartbeat

feeling of warmth

general body swelling

increased sweating

increased thirst


large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs


muscle aches

muscle tremors

muscle weakness


noisy breathing


numbness or tingling in the hands, feet, or lips

pains in the stomach, side, or abdomen, possibly radiating to the back

pale skin

pinpoint red spots on the skin

pounding in the ears

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

rapid, deep or shallow breathing

redness of the face, neck, arms, and occasionally, upper chest



severe constipation

severe sleepiness

severe vomiting

skin blisters

skin rash, hives, or welts


sore throat

stomach cramps

sunken eyes


swelling of the face, fingers, lower legs, or ankles


tightness in the chest



weakness or heaviness of the legs

weight gain

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Bluish lips or skin

change in consciousness

cold, clammy skin

extreme sleepiness

general feeling of discomfort or illness

loss of consciousness

low blood pressure or pulse

slow breathing


Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Relaxed and calm feeling

Incidence not known

Acid or sour stomach


bad, unusual or unpleasant (after) taste


change in taste

cold sweats

constricted, pinpoint, or small pupils (black part of the eye)

continuing ringing or buzzing or other unexplained noise in the ears

cool, pale skin



difficulty with moving

disturbed color perception

double vision

excess air or gas in the stomach or intestines

false or unusual sense of well-being

flushed, dry skin

fruit-like breath odor

full feeling

general feeling of discomfort or illness

halos around lights

hearing loss


increased hunger

increased urination


joint pain

lack or loss of strength

muscle cramps or spasms

muscle pain or stiffness

night blindness


overbright appearance of lights

seeing, hearing, or feeling things that are not there



sleepiness or unusual drowsiness

slurred speech

stomach discomfort, upset, or pain


swollen joints


trouble sleeping

tunnel vision

unexplained weight loss

unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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