What should I watch for?
Visit your doctor or health care professional for regular checks on your progress. You will need lab work done every month while you take this medicine.
This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.
Interactions with Medications
Gold compounds have been shown to cause tumors and cancer of the kidney when given to animals in large amounts for a long time. However, these effects have not been reported in humans receiving gold compounds for arthritis. If you have any questions about this, check with your doctor.
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Irritation or soreness of tongue—less common with auranofin
metallic taste—less common with auranofin
redness, soreness, swelling, or bleeding of gums—rare with auranofin
skin rash or itching
ulcers, sores, or white spots on lips or in mouth or throat
Bloody or cloudy urine
Abdominal or stomach pain, cramping, or burning (severe)
bloody or black, tarry stools
difficulty in swallowing
feeling of something in the eye
hallucinations (hearing, seeing, or feeling things that are not there)
irritation of nose, throat, or upper chest area, possibly with hoarseness or coughing
irritation of vagina
numbness, tingling, pain, or weakness, especially in the face, hands, arms, or feet
painful or difficult urination
pain in lower back, side, or lower abdomen (stomach) area
pinpoint red spots on skin
problems with muscle coordination
red, thickened, or scaly skin
swelling of face, fingers, ankles, lower legs, or feet
swellings (large) on face, eyelids, mouth, lips, and/or tongue
swollen and/or painful glands
unusual bleeding or bruising
unusual tiredness or weakness
vomiting of blood or material that looks like coffee grounds
yellow eyes or skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common with auranofin; rare with injections
Abdominal or stomach cramps or pain (mild or moderate)
bloated feeling, gas, or indigestion (mild or moderate)
decrease or loss of appetite
diarrhea or loose stools
nausea or vomiting (mild or moderate)
Some patients receiving auranofin have noticed changes in the taste of certain foods. If you notice a metallic taste while receiving any gold compound, check with your doctor as soon as possible. If you notice any other taste changes while you are taking auranofin, it is not necessary to check with your doctor unless you find this effect especially bothersome.
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.