What should I watch for?
Improvements to your skin may occur after the first few weeks of treatment. Even though your skin looks better, it is important to keep using the cream as instructed by your health care provider. If you do not notice an improvement in your condition within 6 weeks or if your condition gets worse, tell your health care professional.
Avoid sunlight, sun lamps, tanning beds and treatment with UVA or UVB light while using this medicine. If you need to be outdoors after applying the cream, wear loose fitting clothing that protects the treated area from the sun. Ask your health care provider what other type of sun protection you should use.
Do not cover the skin being treated with bandages, dressings, or wraps. Unless otherwise instructed by your health care provider, do not apply another type of skin product on top of this medicine. However, you can wear normal clothing over the treated areas.
Do not bathe, shower, or swim right after applying this medicine. This could wash off the cream.
While you are using this medicine, drinking alcohol may cause the skin or face to become flushed or red and feel hot. Let your doctor or health care professional know if you notice such reactions.
Interactions with Medications
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Abdominal or stomach pain
body aches or pain
burning, itching, redness, skin rash, swelling, or soreness at the application site
change in hearing
congestion (ear or nasal)
cough producing mucus
difficulty with breathing or shortness of breath
dryness or soreness of the throat
general feeling of discomfort or illness
loss of appetite
loss of voice
muscle aches and pains
tender, swollen glands in the neck
tightness in the chest
trouble with swallowing
trouble with sleeping
unusual tiredness or weakness
warmth on the skin
Blistering, crusting, irritation, itching, or reddening of the skin
blurred vision or other change in vision
itchy, raised, round, smooth, skin-colored bumps found on just one area of the body that are oozing, thick, white fluid
joint pain, stiffness or swelling
redness of the eye
redness of the skin
sensitivity of the eyes to light
skin rash on the face, scalp, or stomach
swelling of the eyelids, face, lips, hands, or feet
troubled breathing or swallowing
Incidence not known
Black, tarry stools
change in size, shape, or color of existing mole
itching, puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
large, hive-like swelling on the face
mole that leaks fluid or bleeds
small, red skin lesion, growth, or bump usually on the face, ears, neck, hands, or arms
sores that will not heal
yellow eyes and skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Blemishes on the skin
burning or stinging of the skin
difficulty having a bowel movement (stool)
flushing; redness of skin; unusually warm skin at site
painful cold sores or blisters on the lips, nose, eyes, or genitals
redness or swelling in the ear
vaginal pain and cramps
Incidence not known
Burning, stinging, itching, or mild discomfort of the eye (after applying the cream to the eyelids or near the eyes)
feeling of warmth (with alcohol use)
redness of the face, neck, arms, and occasionally, upper chest (with alcohol use)
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.