Specialty Drug


Neumega is part of the Megakaryocyte Growth Factors class and treats Chronic ITP. Megakaryocyte growth factors are used to treat chronic ITP. They work by increasing the number of blood platelets to promote normal clotting. Neumega is only available as a brand name drug. Compare megakaryocyte growth factors.

What is Oprelvekin?

Commonly Used Brand Name(s)Neumega

Therapeutic ClassificationsHematopoietic

Pharmacologic ClassificationsInterleukin




Oprelvekin is a synthetic (man-made) version of a substance called interleukin-11. Naturally occurring interleukin-11 is produced by bone marrow cells in the body and helps to make platelets, which are necessary for proper clotting of blood. Oprelvekin is used to help prevent low platelet counts caused by treatment with some cancer medicines.

This medicine is available only with your doctor's prescription.

Proper UseTOP

If you are injecting this medicine yourself, each package of oprelvekin will contain a patient instruction sheet. Read this sheet carefully and make sure you understand:

  • How to prepare the injection.
  • Proper use of disposable syringes.
  • How to give the injection.
  • How long the injection is stable.

If you have any questions about any of this, check with your health care professional.

This medicine works best if it is given at the same time every day.


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

Missed DoseTOP

If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Use & StorageTOP

Store in the refrigerator. Do not freeze.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Before UsingTOP

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Oprelvekin has caused joint and tendon problems in animals and there is a possibility it could also cause these effects in children receiving it. Discuss these possible effects with your doctor.


This medicine has been tested and has not been shown to cause different side effects or problems in older people than it does in younger adults.


Pregnancy CategoryExplanation
All TrimestersCAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast FeedingTOP

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug InteractionsTOP

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Other InteractionsTOP

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical ProblemsTOP

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Congestive heart failure—May be worsened because oprelvekin causes the body to retain water
  • Atrial arrhythmias (heart rhythm problems)—This medicine may cause heart rhythm problems
  • Fluid build-up in the abdomen or lungs—May be worsened by oprelvekin
  • Myeloablative chemotherapy— May lead to serious side effects


It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly and to check for unwanted effects.

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