omeprazole (Prilosec)

Proton Pump Inhibitors

Omeprazole is a proton pump inhibitor (PPI) which works by reducing acid in the stomach. It is used to treat GERD, heartburn, duodenal ulcers and gastric ulcers. It is also approved for use in combination with antibiotics for the treatment of Helicobacter pylori (H. pylori) infection. Omeprazole is available as brand name Prilosec, and over-the-counter as Prilosec OTC.

Side effects of omeprazole

Choose your form:

It can take several days before your stomach pain gets better. Check with your doctor or health care professional if your condition does not start to get better, or if it gets worse.

You may need blood work done while you are taking this medicine.

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Rare

Back, leg, or stomach pain

bleeding or crusting sores on the lips

blisters

bloody or cloudy urine

chills

continuing ulcers or sores in the mouth

difficult, burning, or painful urination

fever

frequent urge to urinate

general feeling of discomfort or illness

joint pain

loss of appetite

muscle aches or cramps

pain

red or irritated eyes

redness, tenderness, itching, burning, or peeling of the skin

skin rash or itching

sore throat

sores, ulcers, or white spots on the lips, in the mouth, or on the genitals

unusual bleeding or bruising

unusual tiredness or weakness

Incidence not known

Drowsiness

fast, racing, or uneven heartbeat

mood or mental changes

muscle spasms (tetany) or twitching seizures

nausea or vomiting

trembling

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Blurred vision

confusion

dryness of the mouth

flushing

headache

increased sweating

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Body aches or pain

chest pain

constipation

cough

diarrhea or loose stools

difficulty with breathing

dizziness

ear congestion

gas

heartburn

loss of voice

muscle pain

nasal congestion

runny nose

sneezing

unusual drowsiness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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