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Ocriplasmin
Specialty Drug

Jetrea

OCRIPLASMIN is an injectable medicine for the eye. It is used to treat vitreomacular adhesion with symptoms. Compare VEGF antibodies.
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What is Ocriplasmin?

Commonly Used Brand Name(s)Jetrea

Therapeutic ClassificationsOphthalmologic Agent

Pharmacologic ClassificationsProteolytic Enzyme

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OverviewTOP

Ocriplasmin injection is used to treat symptomatic vitreomacular adhesion. Symptomatic vitreomacular adhesion is an eye condition related to aging that may lead to blurring of vision or blindness.

This medicine is only administered by or under the supervision of your doctor.

Proper UseTOP

An eye doctor will give you this medicine as a shot into the eye.

Before UsingTOP

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

AllergiesTOP

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

PediatricTOP

Appropriate studies have not been performed on the relationship of age to the effects of ocriplasmin injection in the pediatric population. Safety and efficacy have not been established.

GeriatricTOP

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of ocriplasmin injection in the elderly.

PregnancyTOP

Pregnancy CategoryExplanation
All TrimestersCAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast FeedingTOP

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug InteractionsTOP

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Other InteractionsTOP

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical ProblemsTOP

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Detached retina (eye disorder) or
  • Dyschromatopsia (color vision disorder) or
  • Eye infection or
  • Glaucoma (increased pressure in the eye) or
  • Lens subluxation (partial dislocation of the eye lens)—Use with caution. May make these conditions worse.

PrecautionsTOP

Your eye doctor will want to check your progress at regular visits, especially during the first few days after you receive this medicine.

Serious eye problems may occur with this medicine. Check with your eye doctor right away if your eye becomes red, sensitive to light, or painful, or if you have a change in vision, or feel increased pressure in the eye several days after the injection.

This medicine may cause temporary blurred vision. Avoid driving, using machines, or doing anything else that could be dangerous if you are not able to see well. If this symptom persists, have your eyes checked by an eye doctor.

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