POSACONAZOLE is an antifungal medicine. It is used to treat or prevent certain kinds of fungal or yeast infections. Compare azole antifungals.

Noxafil Side Effects

What should I watch for?

Visit your doctor for regular check ups. Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse. Some fungal infections can take many weeks or months of treatment to cure.

If you get severe diarrhea or vomiting tell your doctor right away. You may not get your full dose of medicine if you are sick.


Interactions with Medications

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Abdominal or stomach pain

black, tarry stools

bloody nose

blurred vision

body aches or pain




difficult or labored breathing

dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position


fever or chills

fruit-like breath odor

heavy non-menstrual vaginal bleeding

increased thirst or urination

irregular heartbeats

loss of voice

muscle pain, spasms, or twitching

nausea or vomiting

numbness or tingling in the hands, feet, lips, mouth, or fingertips

painful cold sores or blisters on the lips, nose, eyes, or genitals

painful or difficult urination

pounding in the ears

slow or fast heartbeat

small red or purple spots on the skin

sores, ulcers, or white spots on the lips, tongue, or inside the mouth


tender, swollen glands in the neck

tightness in the chest


trouble swallowing

unexplained weight loss

yellow eyes or skin

Less common


irregular heartbeat, recurrent

Incidence not known


change in mental status

chest pain or discomfort

darkening of the skin

itching or skin rash

mental depression


sudden shortness of breath or troubled breathing

swelling of the eyes or eyelids

swelling of the face, fingers, feet, or lower legs


Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Acid or sour stomach

back pain


difficulty having a bowel movement (stool)


muscle stiffness

pain in the joints

trouble sleeping

Less common

Bad, unusual, or unpleasant (after) taste

change in taste

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

GoodRx is not sponsored by or affiliated with any of the pharmacies identified in its price comparisons. All trademarks, brands, logos and copyright images are property of their respective owners and rights holders and are used solely to represent the products of these rights holders. This information is for informational purposes only and is not meant to be a substitute for professional medical advice, diagnosis or treatment. GoodRx is not offering advice, recommending or endorsing any specific prescription drug, pharmacy or other information on the site. GoodRx provides no warranty for any of the pricing data or other information. Please seek medical advice before starting, changing or terminating any medical treatment.
The information contained in the Truven Health Micromedex products as delivered by GoodRx is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.
The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and GoodRx make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products.