AMIODARONE is an antiarrhythmic drug. It helps make your heart beat regularly. Because of the side effects caused by this medicine, it is only used when other medicines have not worked. Compare antiarrhythmics.

Nexterone Side Effects

What should I watch for?

Your condition will be monitored closely when you first begin therapy. This drug is first started in a hospital or other monitored health care setting. Once you are on maintenance therapy, visit your doctor or health care professional for regular checks on your progress. Because your condition and use of this medicine carry some risk, it is a good idea to carry an identification card, necklace or bracelet with details of your condition, medications, and doctor or health care professional.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.

This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.

Your eyes may get dry while you are using this medicine. It may be helpful to use a lubricating eye solution or artificial tears solution. Check with your doctor or health care professional for regular eye examinations.

If you are going to have surgery or a procedure that requires contrast dyes, tell your doctor or health care professional that you are taking this medicine.


Interactions with Medications

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

Blurred vision


dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly


unusual tiredness or weakness

Less common

Black, tarry stools

bleeding gums

blistering, peeling, or loosening of the skin

blood in the urine or stools

chest pain or discomfort


cold, clammy skin


decreased urine output


difficulty with breathing

dilated neck veins


extreme fatigue


fast, pounding, or irregular heartbeat or pulse

fast, weak pulse


irregular heartbeat recurrent


joint or muscle pain

lightheadedness, dizziness, or fainting

no blood pressure or pulse

pinpoint red spots on the skin

red, irritated eyes

red skin lesions, often with a purple center

shortness of breath

slow or irregular heartbeat

sore throat

sores, ulcers, or white spots in the mouth or on the lips

stopping of the heart

swelling of the face, fingers, feet, or lower legs

tightness in the chest

troubled breathing


unusual bleeding or bruising

weight gain


Incidence not known

Abdominal or stomach pain


back, leg, or stomach pains

bleeding gums


blurred or double vision

clay-colored stools


confusion about identity, place, and time

cough or hoarseness

coughing or spitting up blood

cracks in the skin

dark-colored urine

decreased frequency or amount of urine

decreased urine output


difficulty swallowing

eye pain

fever with or without chills

general body swelling

general feeling of tiredness or weakness


high fever


holding false beliefs that cannot be changed by fact


increased blood pressure

increased thirst


inflamed tissue from infection


large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs


light-colored stools

loss of appetite

loss of heat from the body

lower back or side pain

muscle cramps or spasms

muscle pain or stiffness

muscle twitching

muscular pain, tenderness, wasting, or weakness

noisy breathing


painful or difficult urination

pains in the stomach, side, or abdomen, possibly radiating to the back

pale skin

persistent non-healing sore

pink growth

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

rapid weight gain


red, swollen skin

reddish patch or irritated area

redness, soreness, or itching skin

scaly skin

seeing, hearing, or feeling things that are not there


severe headache

shiny bump

sores, welting, or blisters


swollen or painful glands

unexplained bleeding or bruising

unpleasant breath odor

unusual excitement, nervousness, or restlessness

upper right abdominal pain


vomiting of blood


white, yellow, or waxy scar-like area

yellow eyes and skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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