What should I watch for?
Visit your doctor or health care professional for regular checks on your progress. You may need blood work done while you are taking this medicine. If you are going to need surgery, be sure to tell your doctor before the procedure is scheduled. Do not stop taking except on your doctor's advice.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
Tell your doctor immediately if you get a serious injury, serious infection, or any serious illness requiring a hospital visit or emergency care, including trauma. Mitotane should be stopped until you recover.
Try to avoid people who are sick during your treatment. Do not have any vaccinations without your doctor's approval and avoid anyone who has recently had oral polio vaccine.
Do not become pregnant while taking this medicine. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. The use of effective birth control is advised. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine.
Interactions with Medications
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Darkening of the skin
dizziness or lightheadedness
loss of appetite
nausea or vomiting
unusual tiredness or weakness
Blood in the urine
Shortness of breath
Incidence not known
dizziness, faintness, or lightheadedness when getting up from a lying or sitting position
feeling of warmth
lower abdominal or stomach cramping
pounding in the ears
redness of the face, neck, arms, and occasionally, upper chest
slow or fast heartbeat
white area over the eye
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Feeling of constant movement of self or surroundings
passing of gas
sensation of spinning
stomach pain, fullness, or discomfort
unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
flushing or redness of the skin
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.