METYRAPONE is a diagnostic aid. It is used to test if the adrenal glands are working properly. Compare medical supplies and devices.

Metyrapone Side Effects

What should I watch for?

Visit your doctor or health care professional for regular checks on your health. Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.


Interactions with Medications

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Rare (with long-term use)

Irregular heartbeat

Check with your doctor as soon as possible if any of the following side effects occur:

Less common

Skin rash

Rare (usually with long-term use)

Enlargement of clitoris

muscle cramps or pain

sore throat or fever

swelling of feet or lower legs

unusual bleeding or bruising

unusual tiredness or weakness

weight gain (rapid)

Symptoms of overdose

Abdominal or stomach pain (severe)


decrease in consciousness

diarrhea (severe)

nausea (severe)


unusual thirst

vomiting (severe)

weakness (sudden)

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common







Confusion or mental slowing

excessive hair growth

greater-than-normal loss of scalp hair

increased sweating

loss of appetite

upper abdominal or stomach pain


worsening of acne

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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