Generic Levo-Dromoran

Levorphanol is a pain reliever. It is used to treat moderate to severe pain. Compare opioids.

Levorphanol Side Effects

What should I watch for?

Tell your doctor or health care professional if your pain does not go away, if it gets worse, or if you have new or a different type of pain. You may develop tolerance to the medicine. Tolerance means that you will need a higher dose of the medicine for pain relief. Tolerance is normal and is expected if you take this medicine for a long time.

Do not suddenly stop taking your medicine because you may develop a severe reaction. Your body becomes used to the medicine. This does NOT mean you are addicted. Addiction is a behavior related to getting and using a drug for a non-medical reason. If you have pain, you have a medical reason to take pain medicine. Your doctor will tell you how much medicine to take. If your doctor wants you to stop the medicine, the dose will be slowly lowered over time to avoid any side effects.

There are different types of narcotic medicines (opiates). If you take more than one type at the same time or if you are taking another medicine that also causes drowsiness, you may have more side effects. Give your health care provider a list of all medicines you use. Your doctor will tell you how much medicine to take. Do not take more medicine than directed. Call emergency for help if you have problems breathing or unusual sleepiness.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.

This medicine will cause constipation. Try to have a bowel movement at least every 2 to 3 days. If you do not have a bowel movement for 3 days, call your doctor or health care professional.

Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe.


Interactions with Medications

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Incidence not known


attempts at killing oneself

bluish lips or skin

blurred vision

change in consciousness

cold, clammy skin


decrease in the frequency of urination

decrease in urine volume

decreased urine output


difficulty in passing urine (dribbling)

dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

extra heartbeats

extremely shallow or slow breathing

fast, slow, irregular, pounding, or racing heartbeat or pulse

fast, weak pulse




loss of consciousness

muscle twitching

no blood pressure or pulse

not breathing

painful urination

rapid weight gain


stopping of the heart



swelling of the face, ankles, or hands


unusual tiredness or weakness


Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Chest pain or discomfort

constricted, pinpoint, or small pupils (black part of the eye)

decreased awareness or responsiveness

difficult or troubled breathing

difficulty with sleeping

dilated neck veins


drowsiness to profound coma

extreme fatigue



irregular, fast or slow, or shallow breathing

no muscle tone or movement

not breathing

pale or blue lips, fingernails, or skin

shortness of breath

sleepiness or unusual drowsiness

swelling of the face, fingers, feet, or lower legs

weight gain

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

Abnormal dreams

absence of or decrease in body movement

acid or sour stomach


change in personality

changes in vision




double vision

dry mouth

feeling sad or empty


hives or welts

increase in body movements




lack of appetite

loss of interest or pleasure

loss of memory



problems with memory

redness of the skin

seeing double

skin rash

stomach discomfort, upset, or pain



trouble concentrating

trouble sleeping

twitching, twisting, uncontrolled repetitive movements of the tongue, lips, face, arms, or legs

upper abdominal or stomach pain


Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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