SGLT2 Inhibitors

Invokana is part of the SGLT2 Inhibitors class and treats Diabetes Type 2. SGLT2 Inhibitors are used to treat diabetes type 2. They work by removing excess glucose by blocking reabsorption through the kidneys. Invokana is only available as a brand name drug.

Side effects of Invokana

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Bladder pain

bloody or cloudy urine

decreased frequency or amount of urine

difficult, burning, or painful urination

discharge with a strong odor from the penis

frequent urge to urinate

increased blood pressure

increased thirst

itching of the vagina or outside of the genitals

loss of appetite

lower back or side pain


pain during sexual intercourse

pain in the skin around the penis

redness, itching, or swelling of the penis

swelling of the face, fingers, or lower legs

troubled breathing

unusual tiredness or weakness

vaginal discharge without odor or with mild odor


weight gain

Less common


blurred vision


cold sweats


cool, pale skin



dry mouth

fast or irregular heartbeat


hives or welts

increased hunger

itching skin

large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs



redness of the skin



slurred speech

unusual tiredness or weakness

Incidence not known

Abdominal or stomach pain

dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

numbness or tingling in the hands, feet, or lips


weakness or heaviness of the legs

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Difficulty having a bowel movement (stool)

lack or loss of strength

pain or swelling in the arms or legs without an injury


Increased sensitivity of the skin to sunlight

redness or other discoloration of the skin

severe sunburn

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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