Specialty Drug


AXITINIB is a medicine that targets proteins in cancer cells and stops the cancer cells from growing. It is used to treat kidney cancers. Compare kinase inhibitors.

Inlyta Side Effects

What should I watch for?

Visit your doctor for checks on your progress. Report any new symptoms promptly.

This drug may make you feel generally unwell. This is not uncommon, as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your doctor tells you to stop.

Be careful brushing and flossing your teeth or using a toothpick because you may get an infection or bleed more easily. If you have any dental work done, tell your dentist you are receiving this medicine.

Do not become pregnant while taking this medicine. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Men should inform their doctors if they wish to father a child. This medicine may lower sperm counts. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine.


Interactions with Medications

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Abdominal or stomach pain

bleeding gums

bloody nose

blurred vision

cloudy urine



coughing up blood

decreased urination

depressed mood

difficult or labored breathing

difficulty with swallowing


dry mouth

dry skin and hair


feeling cold

hair loss

hoarseness or husky voice

incoherent speech

increased menstrual flow or vaginal bleeding

increased urination


loss of appetite

metallic taste

muscle cramps and stiffness

muscle weakness





pounding in the ears

rapid breathing

red or black, tarry stools

red or dark brown urine

redness, swelling, or pain of the skin

scaling of the skin on the hands and feet

slow or fast heartbeat

sunken eyes


tightness in the chest

tingling of the hands and feet

ulceration of the skin

unusual tiredness or weakness


weight gain or loss

wrinkled skin

Less common


bleeding from the gums or nose

bleeding from the rectum

bloody, black or tarry stools

change in vision

chest pain or discomfort

extreme drowsiness

eye pain


inability to speak


numbness or tingling in the face, arms, hands, or legs

pain in the chest, groin, or legs

pain or discomfort in the arms, jaw, back, or neck

pain, redness, or swelling in the arm or leg

pale skin

ringing in the ears


sensitivity to heat

severe headaches of sudden onset

severe stomach pain, cramping, or burning

slurred speech

sudden loss of coordination

sudden onset of slurred speech

sudden shortness of breath or troubled breathing

sudden vision changes


temporary blindness

trouble sleeping

trouble speaking, thinking, or walking

troubled breathing with exertion

uncomfortable swelling around the anus

unusual bleeding or bruising

vomiting of material that looks like coffee grounds

weakness in the arm or leg on one side of the body

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common


change in taste


cracked lips

decreased appetite


difficulty with moving

itching skin or rash

joint pain

lack or loss of strength

loss of taste

muscle aches or pain

pain in the arms or legs

sore throat

sores, ulcers, or white spots on the lips, tongue, or inside the mouth

stomach discomfort or upset

swelling or inflammation of the mouth

swollen joints

upper stomach pain

voice changes

Less common

Burning sensation of the tongue

continuous ringing or buzzing or other unexplained noise in the ears

flushing or redness of the skin

hearing loss

thinning of the hair

unusually warm skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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