Specialty Drug
IMMUNE GLOBULIN helps to prevent or reduce the severity of certain infections in patients who are at risk. This medicine is collected from the pooled blood of many donors. It is used to treat immune system problems, thrombocytopenia, and Kawasaki syndrome. Compare human immunoglobulin gs.

Hizentra Side Effects

What should I watch for?

Your condition will be monitored carefully while you are receiving this medicine.

This medicine is made from pooled blood donations of many different people. It may be possible to pass an infection in this medicine. However, the donors are screened for infections and all products are tested for HIV and hepatitis. The medicine is treated to kill most or all bacteria and viruses. Talk to your doctor about the risks and benefits of this medicine.

Do not have vaccinations for at least 14 days before, or until at least 3 months after receiving this medicine.


Interactions with Medications

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common



fast, pounding, or irregular heartbeat or pulse


noisy breathing

tightness in the chest

troubled breathing

unusual tiredness or weakness

Less common

Bluish coloring of the lips or nail beds

burning sensation in the head

faintness or lightheadedness


Difficulty with swallowing

hives or welts

itching, especially of the feet or hands

reddening of the skin, especially around the ears

swelling of the eyes, face, or inside of the nose

Incidence not known

Back, leg, or stomach pains

blistering, peeling, or loosening of the skin

change in vision

changes in urination

chest pain or discomfort

cold, clammy, or pale skin



dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position


headache that is severe and occurs suddenly

light-colored stools

loss of consciousness

low blood pressure or pulse

muscle spasm or jerking of all extremities

nausea or vomiting

pains in the chest, groin, or legs, especially calves of the legs

shakiness in the legs, arms, hands, or feet

skin blisters

slow breathing

slurred speech that occurs suddenly

sores, ulcers, or white spots in the mouth or on the lips

sudden, severe weakness or numbness in the arm or leg


swelling in the legs and ankles

tightness in the chest

unusual bleeding or bruising

yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common




joint pain

muscle pain

redness, swelling, itching, or pain at the injection site

skin rash

Less common

Hip pain

leg cramps

Incidence not known

Feeling of warmth

redness of the face, neck, arms, and occasionally, upper chest

stomach pain

swollen glands



Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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