FIDAXOMICIN is a macrolide antibiotic. It is used to treat certain kinds of bacterial infections in the bowel. It will not work for colds, flu, or other viral infections. Compare macrolide antibiotics.

Fidaxomicin Side Effects

What should I watch for?

Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.

Do not treat diarrhea with over the counter products.


Interactions with Medications

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

Abdominal or stomach pain


bloody or black, tarry stools







loss of appetite

lower back or side pain

muscle tremors


painful or difficult urination

pale skin

rapid, deep breathing


severe constipation

shortness of breath

sore throat

stomach cramps

troubled breathing with exertion

ulcers, sores, or white spots in the mouth

unusual bleeding or bruising

unusual tiredness or weakness


vomiting of blood or material that looks like coffee grounds

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Abdominal or stomach distension or tenderness

acid or sour stomach


blurred vision

difficulty with swallowing

dry mouth

excess air or gas in the stomach or intestines

flushed, dry skin

fruit-like breath odor

full feeling


increased hunger

increased thirst

increased urination


itching skin

passing gas


stomach discomfort or upset


troubled breathing

unexplained weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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