Specialty Drug
DEFERIPRONE binds to iron in the blood. It helps to prevent and treat too much iron in the blood caused by blood transfusions. Compare metal chelators.

Ferriprox Side Effects

What should I watch for?

Visit your doctor for regular check ups. You may need blood work done while taking this medicine.

Your urine might show a red or brown discoloration during treatment. This is a very common sign of the desired effect of this medicine, and it is not harmful.


Interactions with Medications

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Black, tarry stools




lower back or side pain

painful or difficult urination

pale skin

shortness of breath

sore throat

ulcers, sores, or white spots in the mouth

unusual bleeding or bruising

unusual tiredness or weakness

Less common

Fever with or without chills

general feeling of tiredness or weakness


Incidence not known

Abdominal or stomach pain


bleeding gums

bloating or swelling of the face, arms, hands, lower legs, or feet

blood in the urine or stools

blurred vision

chest pain or discomfort

clay-colored stools



dark urine

decreased urination

dilated neck veins

dizziness or lightheadedness

dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position


dry mouth

extreme fatigue


fast or irregular heartbeat



increase in heart rate

increased sweating

irregular breathing



joint pain, stiffness, or swelling

large, flat, blue or purplish patches in the skin

loss of appetite

muscle tremors



painful knees and ankles

pinpoint red spots on the skin

pounding in the ears

raised red swellings on the skin, the buttocks, legs, or ankles

rapid weight gain

rapid, deep breathing

rapid, shallow breathing


redness of the skin


severe nausea or vomiting

slow heartbeat


spots on your skin resembling a blister or pimple

stomach cramps

sudden shortness of breath or troubled breathing

sugar in the urine

sunken eyes


swelling around the eyes

swelling of the eyelids, face, lips, hands, or feet


tightness in the chest

tingling of the hands or feet

trouble with balance

troubled breathing or swallowing

unpleasant breath odor

unusual weight gain or loss

vision changes

vomiting of blood

weight gain

wrinkled skin

yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Abdominal or stomach discomfort

difficulty with moving

muscle pain or stiffness

reddish or brow discoloration of the urine

Less common

Acid or sour stomach

back pain




increased or decreased appetite


pain in the arms or legs

stomach upset

Incidence not known

Bloody nose

clenching, gnashing, or grinding teeth


coughing or spitting up blood


difficulty opening the mouth

difficulty with speaking


hives or welts

impaired psychomotor skills

increased sensitivity of the skin to sunlight


loss of appetite

loss of balance control

muscle spasm, especially of the neck and back

muscle trembling, jerking, or stiffness

pains in the stomach, side, or abdomen, possibly radiating to the back

redness or other discoloration of the skin


severe sunburn

shuffling walk

sleepiness or unusual drowsiness

stiffness of the limbs

stomach bloating, burning, cramping, or pain

twisting movements of the body

uncontrolled movements, especially of the face, neck, and back

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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