RASBURICASE breaks down uric acid in the blood. It is used to prevent and to treat high levels of uric acid caused by cancer treatment. Compare uricosuric drugs.

Elitek Side Effects

What should I watch for?

Your condition will be monitored carefully while you are receiving this medicine. You will need to have regular blood tests during your treatment.


Interactions with Medications

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

Cracked lips


difficulty with swallowing

sores, ulcers, or white spots on the lips, tongue, or inside the mouth

Less common

Abdominal or stomach pain


black or red, tarry, stools

bleeding gums

bluish color of the fingernails, lips, skin, palms, or nail beds

changes in skin color

changes in vision

chest pain or discomfort




convulsions (seizures)


coughing that sometimes produces a pink, frothy sputum

coughing up blood

decreased urination


dilated neck veins


dry mouth


fast, slow, or irregular heartbeat




increased menstrual flow or vaginal bleeding

increased sweating

increased thirst


itching, pain, redness, swelling, tenderness, or warmth on the skin


lower back or side pain

muscle twitching


no blood pressure or pulse


pain or discomfort in the arms, jaw, back, or neck

pain, tenderness, or swelling of the foot or leg

painful or difficult urination

pains in the chest, groin, or legs, especially calves of the legs

pale skin


prolonged bleeding from cuts

red or dark brown urine

severe constipation

severe headaches of sudden onset

shortness of breath

skin rash


sore throat

stopping of heart


sudden loss of coordination

sudden onset of shortness of breath for no apparent reason

sudden onset of slurred speech

sunken eyes


swelling of the face, fingers, feet, or lower legs

swollen glands

temporary blindness


tightness in the chest

troubled breathing


unexplained or unusual bleeding or bruising

unusual tiredness or weakness


weight gain


wrinkled skin


Back pain


itching, puffiness, or swelling of the eyelids or around the eyes, face, lips, or tongue

yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site

burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

feeling of warmth

feeling unusually cold

redness of the face, neck, arms, and occasionally, upper chest


Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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