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Dasatinib
Specialty Drug

Sprycel

DASATINIB is a medicine that targets specific proteins in cancer cells and stops the cancer cells from growing. It is used to treat some kinds of leukemia. Compare kinase inhibitors.
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Dasatinib Side Effects

What should I watch for?

Visit your doctor for regular check ups. Report any side effects. Continue your course of treatment unless your doctor tells you to stop. You will need blood work done while you are taking this medicine.

You may need blood work done while you are taking this medicine.

Do not become pregnant while taking this medicine or for 30 days after stopping it. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine and for 2 weeks after the last dose.

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Interactions with Medications

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Bloody or black, tarry stools

body aches or pain

burning, tingling, numbness or pain in the hands, arms, feet, or legs

chest pain

constipation

cough or hoarseness

coughing up blood

decrease in the amount of urine

dizziness

ear congestion

fainting

fast, slow, or irregular heartbeat

fever or chills

full or bloated feeling

headache

loss of voice

lower back or side pain

nasal congestion

noisy or rattling breathing

painful or difficult urination

pale skin

paralysis

pressure in the stomach

runny nose

sensation of pins and needles

severe stomach pain

sneezing

sore throat

stabbing pain

swelling of the abdominal or stomach area

swelling of the face, fingers, hands, feet, or lower legs

tightness in the chest

troubled breathing

ulcers, sores, or white spots in the mouth

unsteadiness or awkwardness

unusual bleeding or bruising

unusual tiredness or weakness

vomiting of blood or material that looks like coffee grounds

weakness in the arms, hands, legs, or feet

weight gain

Less common

Bloating

blue lips and fingernails

chest discomfort

coughing that sometimes produces a pink frothy sputum

decreased urine output

difficult or fast breathing

dilated neck veins

increased sweating

irregular breathing

irregular heartbeat

nausea

swelling

swelling in the legs and ankles

Incidence not known

Anxiety

pain, redness, or swelling in the arm or leg

sudden shortness of breath or troubled breathing

tenderness, pain, swelling, warmth, skin discoloration, and prominent superficial veins over the affected area

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Abdominal or stomach pain

bleeding gums

cracked lips

diarrhea

difficulty with moving

difficulty with swallowing

increased menstrual flow or vaginal bleeding

itching skin or rash

lack or loss of strength

loss of appetite

muscle aching or cramping

muscle or bone pain

muscle stiffness

nose bleeds

pain

pain in the joints

prolonged bleeding from cuts

red or dark brown urine

swollen joints

vomiting

weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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