D.H.E. 45 Coupon - D.H.E. 45 1ml of 1mg/ml ampule

Dihydroergotamine Mesylate

DIHYDROERGOTAMINE is used to treat migraine headaches with or without aura. It should not be used to prevent migraine headaches. Compare ergot derivatives.
D.H.E. 45 Coupon - D.H.E. 45 1ml of 1mg/ml ampule

Potentially Unavailable: This drug has recently experienced shortages and may not be available at your pharmacy. Please call ahead to confirm availability. Learn More


D.H.E. 45 Side Effects

What should I watch for?

Visit your doctor for regular check ups. Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. To reduce dizzy or fainting spells, do not sit or stand up quickly, especially if you are an older patient. Alcohol can increase drowsiness, dizziness and flushing. Avoid alcoholic drinks.


Interactions with Medications

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Less common or rare

Chest pain

cough, fever, sneezing, or sore throat

feeling of heaviness in chest

irregular heartbeat

itching of the skin

numbness and tingling of face, fingers, or toes

pain in arms, legs, or lower back

pain in back, chest or left arm

pale bluish-colored or cold hands or feet

shortness of breath or troubled breathing

weak or absent pulses in legs

Symptoms of overdose


convulsions (seizures)




nausea and/or vomiting

numbness, tingling, and/or pain in the legs or arms

shortness of breath

stomach pain

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Burning or tingling sensation, dryness, soreness, or pain in the nose

change in sense of taste



dry mouth



increased sweating

nausea and or vomiting

muscle stiffness

runny and or stuffy nose

sudden sweatings and feelings of warmth

sensation of burning, warmth, or heat

sore throat


unexplained nose bleeds

unusual tiredness or weakness

Less common


blurred vision

cold clammy skin


congestion in chest


decreased appetite


difficulty swallowing

dizziness or lightheadedness when getting up from a lying or sitting position

ear pain

eye pain



increased watering of eyes

increased watering of the mouth

increased yawning

muscle weakness


pinpoint red spots on skin

pounding heartbeat

red or irritated eyes

ringing or buzzing in ears

skin rash

stomach pain

sudden fainting

swelling of face, fingers, feet, or lower legs

trembling or shaking of hands or feet

trouble in sleeping

unusual feeling of well being

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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