Combipatch Coupon - Combipatch 8 patches of 0.05mg/0.14mg package
ESTRADIOL; NORETHINDRONE contains a mixture of female hormones. This medicine helps to relieve the symptoms of menopause like hot flashes, night sweats, mood changes, and vaginal dryness and irritation. It is also used to treat women with low estrogen levels or those who have had their ovaries removed. Compare estrogen / progestin combinations.
Combipatch Coupon - Combipatch 8 patches of 0.05mg/0.14mg package

Combipatch Side Effects

What should I watch for?

Visit your health care professional for regular checks on your progress. You should have a complete check-up every 6 months. You will need a regular breast and pelvic exam. You should also discuss the need for regular mammograms with your health care professional, and follow his or her guidelines.

This medicine can make your body retain fluid, making your fingers, hands, or ankles swell. Your blood pressure can go up. Contact your doctor or health care professional if you feel you are retaining fluid.

If you have any reason to think you are pregnant; stop taking this medicine at once and contact your doctor or health care professional.

Tobacco smoking increases the risk of getting a blood clot or having a stroke, especially if you are more than 35 years old. You are strongly advised not to smoke.

If you wear contact lenses and notice visual changes, or if the lenses begin to feel uncomfortable, consult your eye care specialist.

If you are going to have elective surgery, you may need to stop taking this medicine beforehand. Consult your health care professional for advice prior to scheduling the surgery.

If you are going to have a MRI procedure, let your MRI technician know about the use of these patches. Some drug patches contain an aluminized backing that can become heated when exposed to MRI and may cause burns. You may need to temporarily remove the patch during the MRI procedure.

You may bathe or participate in other activities while wearing your patch. If the patch pulls loose or falls off, you may reapply it if the patch is sticky enough to stay on the skin. You should reapply the patch in a different area. Otherwise use a fresh patch.


Interactions with Medications

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Bloating or swelling of the face, arms, hands, lower legs, or feet

heavy non-menstrual vaginal bleeding

itching of the vagina or genital area

pain during sexual intercourse

rapid weight gain

thick, white vaginal discharge with no odor or with a mild odor

tingling of the hands or feet

unusual weight gain or loss

Less common

Cough or hoarseness

fever or chills

lower back or side pain

painful or difficult urination

Incidence not known

Abdominal or stomach bloating or fullness

abdominal or stomach pain

blurred vision

change in vaginal discharge

clay-colored stools

clear or bloody discharge from the nipple

dark urine


dimpling of the breast skin


gaseous abdominal or stomach pain

headache, severe and throbbing



inverted nipple



joint pain, stiffness or swelling

large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

loss of appetite

lump in the breast or under the arm

nausea and vomiting


pain or feeling of pressure in the pelvis

persistent crusting or scaling of the nipple

pounding in the ears


recurrent fever

redness of the skin

redness or swelling of the breast

severe cramping of the uterus

slow or fast heartbeat

sore on the skin of the breast that does not heal

swelling of the eyelids, face, lips, hands, or feet

tightness in the chest

troubled breathing or swallowing

unpleasant breath odor

unusual tiredness or weakness

vaginal bleeding

vomiting of blood

yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Acid or sour stomach

back pain


body aches or pain

breast pain

burning, itching, redness, skin rash, swelling, or soreness at the application site



difficulty with moving


dryness or soreness of the throat

excess air or gas in the stomach or intestines

feeling sad or empty

general feeling of discomfort or illness



heavy bleeding

increased clear or white vaginal discharge



lack or loss of strength

loss of interest or pleasure

muscle aches and pains

muscle stiffness

pain during sexual intercourse

pain or tenderness around the eyes and cheekbones

passing gas



stomach discomfort or upset

stuffy or runny nose


tender, swollen glands in the neck

thick, white vaginal discharge with no odor or with a mild odor


trouble concentrating

trouble sleeping

Less common

Blemishes on the skin

difficulty having a bowel movement (stool)

longer or heavier menstrual periods


Incidence not known

Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

change in color of the treated skin

decreased interest in sexual intercourse

dizziness or lightheadedness

dull ache or feeling of pressure or heaviness in the legs

feeling of constant movement of self or surroundings

inability to have or keep an erection

increased in sexual ability, desire, drive, or performance

increased interest in sexual intercourse

itching skin near damaged veins

loss in sexual ability, desire, drive, or performance

sensation of spinning

weight gain

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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