What should I watch for?
This drug may make you feel generally unwell. This is not uncommon, as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your doctor tells you to stop.
In some cases, you may be given additional medicines to help with side effects. Follow all directions for their use.
This drug can cause vomiting and diarrhea which may lead to dehydration. Signs and symptoms of dehydration include dizziness, lightheadedness, fainting spells, or decreased urine output. If you notice any of these symptoms, call your doctor immediately.
Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. Do not treat yourself. This drug decreases your body's ability to fight infections. Try to avoid being around people who are sick.
This medicine may increase your risk to bruise or bleed. Call your doctor or health care professional if you notice any unusual bleeding.
Be careful brushing and flossing your teeth or using a toothpick because you may get an infection or bleed more easily. If you have any dental work done, tell your dentist you are receiving this drug.
This drug quickly kills leukemia cells which may result in a syndrome called 'tumor lysis syndrome'. If you experience symptoms such as fast breathing, fast heartbeat, dizziness, and difficulty breathing, call your doctor immediately.
Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine.
Interactions with Medications
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
Abdominal or stomach pain or tenderness
black, tarry stools
blood in the urine or stools
burning or stinging of the skin
cough or hoarseness
decreased urine output
difficult or labored breathing
dilated neck veins
dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
fast, pounding, or irregular heartbeat or pulse
feeling of warmth
flushing, redness of the skin
itching in the genital area
joint pain, stiffness, or swelling
loss of appetite
lower back or side pain
painful cold sores or blisters on the lips, nose, eyes, or genitals
painful or difficult urination
pinpoint red spots on the skin
pounding in the ears
rapid, shallow breathing
redness of the face, neck, arms, and occasionally, upper chest
redness, swelling, or skin pain
scaling of the skin on the hands and feet
severe abdominal or stomach cramps with pain
slow or fast heartbeat
small red or purple spots on the skin
sores, ulcers, or white spots on the lips or in the mouth
swelling of the ankles, feet, or lower legs
swelling or inflammation of the mouth
tightness in the chest
tingling of the hands and feet
troubled breathing with exertion
ulcers, sores, or white spots in the mouth
unpleasant breath odor
unusual bleeding or bruising
unusual tiredness or weakness
unusually warm skin
vomiting of blood
warmth on the skin
watery and severe diarrhea, which may also be bloody
yellow eyes or skin
blue lips and fingernails
chest pain or discomfort
coughing that sometimes produces a pink frothy sputum
decrease or increase in the amount of urine
decreased level of consciousness
difficult, fast, or noisy breathing, sometimes with wheezing
general feeling of discomfort or illness
muscle aches and pains
pain or tenderness around the eyes and cheekbones
pains in the stomach, side, or abdomen, possibly radiating to the back
rapid weight gain
stuffy or runny nose
swelling of the eyelids, face, lips, or hands
Incidence not known
Blistering, peeling, or loosening of the skin
red irritated eyes
red skin lesions, often with a purple center
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
bruises on the skin
difficulty with moving
difficulty with swallowing
feeling sad or empty
feeling unusually cold
injection site pain
lack or loss of strength
loss of interest or pleasure
muscle pain or stiffness
pain in the limbs
pain in the rectum
right upper stomach pain and fullness
sore mouth or tongue
unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
unusually warm skin
white patches with diaper rash
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.