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Bupivacaine is part of the Local Anesthetics class and treats Pain and Anesthesia. Local anesthetics are used as anesthesia and to treat pain, postherpetic neuralgia, and ear infections. They work by blocking pain signals in the nerves. Bupivacaine is only available as a generic drug. Compare local anesthetics.
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Bupivacaine Side Effects

Interactions with Medications

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

Bloating or swelling of the face, arms, hands, lower legs, or feet

blurred vision

confusion

dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

fast, pounding, or irregular heartbeat or pulse

fever

pale skin

rapid weight gain

sweating

tingling of the hands or feet

troubled breathing with exertion

unusual bleeding or bruising

unusual tiredness or weakness

unusual weight gain or loss

Less common

Bleeding from the anus

burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

chest pain or discomfort

fainting

lightheadedness, dizziness, or fainting

painful defecation

shortness of breath

slow or irregular heartbeat

swelling at the surgical site

Less common or rare

Chills

decrease in the frequency of urination

decrease in the urine volume

difficult or troubled breathing

difficulty in passing urine (dribbling)

extra heart beat

headache

hives

hoarseness

irregular, fast or slow, or shallow breathing

irritation

itching

joint pain, stiffness, or swelling

nervousness

not breathing

painful urination

pale or blue lips, fingernails, or skin

pounding in the ears

rash

redness of the skin

shakiness in the legs, arms, hands, or feet

shortness of breath

swelling at the incision site

tightness in the chest

troubled breathing or swallowing

weakness

wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Back pain

muscle spasm

nausea

sleepiness or unusual drowsiness

sleeplessness

trouble sleeping

unable to sleep

vomiting

Less common

Decreased appetite

itching in the genital or other skin areas

scaling

unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness

Less common or rare

Agitation

cold sweats

hives or welts

increased sweating

muscle weakness

pain in the neck

paleness of the skin

restlessness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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