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What is Juvisync? A match made in heaven in a new diabetes and cholesterol combination pill.

by Dr. Sharon Orrange on January 11, 2012 at 2:12 pm

A new combination pill targeted at diabetes and cholesterol is hitting the market and you will be hearing about it. Juvisync is a combination medication that contains two previously approved medicines: the generic cholesterol medication simvastatin, and Januvia (sitagliptin) a diabetes medication.

What are the upsides of Juvisync?

1) First off, you kill two birds with one stone and treat diabetes and cholesterol in one pill.

2) The diabetes medication Januvia (sitagliptin) enhances the body’s own ability to lower elevated blood glucose.

3) Januvia, unlike some other diabetes medications, does not cause low blood sugar (hypoglycemia) making it a preferable option to diabetes drugs that do cause low sugar (glyburide or glipizide).

4) Simvastatin works well to lower your LDL cholesterol.

5) Juvisync will come with 100 mg of Januvia mixed with three choices of simvastatin doses: 10 mg/100 mg, 20 mg/100 mg and 40 mg/100 mg.

What are the downsides of Juvisync?

1) Januvia is not yet recognized as a first line treatment for diabetes. Glucophage (metformin) is usually the first line oral diabetes medication.

2) Cases of pancreatitis have been reported with Januvia, though it is a rare complication.

3) As with any combination drug, if you have a side effect, we don’t know which medication is the culprit.

4) It will most likely be expensive. Simvastatin is cheap alone but mixed with Januvia I imagine your copayment will be higher.

Jump in with your thoughts.

Dr. O.

Generic simvastatin should be covered by most insurance plans as a Tier 1 generic, meaning you’ll pay your minimum copay. Simvastatin may also be available for as little as $4 for a 30-day supply. Januvia and Juvisync are typically considered Tier 2 or 3 drugs by many insurance plans, meaning you’ll pay a moderate to high copay. Januvia is typically $200 – $300 out of pocket for a 30-day supply, and according to the manufacturer Juvisync will be similarly priced. You can find Juvisync prescription savings and free trial information on the Juvisync website.

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