Arthrotec Coupon - Arthrotec 50mg/200mcg tablet

Diclofenac Sodium/Misoprostol

DICLOFENAC; MISOPROSTOL is a combination of two different drugs. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID). It is used to reduce swelling and to treat pain. Misoprostol protects the stomach against ulcers. This medicine is used for arthritis in people who are at high risk for stomach ulcers from NSAID treatment. Compare NSAID / prostaglandin combinations.
Arthrotec Coupon - Arthrotec 50mg/200mcg tablet

Arthrotec Side Effects

What should I watch for?

Tell your doctor or health care professional if your pain does not get better. Talk to your doctor before taking another medicine for pain. Do not treat yourself.

This medicine does not prevent heart attack or stroke. In fact, this medicine may increase the chance of a heart attack or stroke. The chance may increase with longer use of this medicine and in people who have heart disease. If you take aspirin to prevent heart attack or stroke, talk with your doctor or health care professional.

Do not take medicines such as ibuprofen and naproxen with this medicine. Side effects such as stomach upset, nausea, or ulcers may be more likely to occur. Many medicines available without a prescription should not be taken with this medicine.

This medicine can cause ulcers and bleeding in the stomach and intestines at any time during treatment. Do not smoke cigarettes or drink alcohol. These increase irritation to your stomach and can make it more susceptible to damage from this medicine. Ulcers and bleeding can happen without warning symptoms and can cause death.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.

This medicine can cause you to bleed more easily. Try to avoid damage to your teeth and gums when you brush or floss your teeth.

If you are female, do not use this medicine if you are pregnant. Do not get pregnant while taking this medicine and for at least one month (one full menstrual cycle) after stopping this medicine. If you can have children, use a reliable form of birth control while taking this medicine. Talk to your doctor about birth control options. If you become pregnant, think you are pregnant, or want to become pregnant, immediately call your doctor for advice.


Interactions with Medications

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

Black, tarry stools

bleeding or crusting sores on the lips

blood in the urine or stools

bruises or red spots on the skin

chest pain



continuing thirst

convulsions (seizures)

cough or hoarseness




fever with or without chills

fluid retention

general feeling of illness

heartburn or indigestion

increased heart rate

increased weight gain

irregular heartbeat

itching of the skin

large, flat, blue or purplish patches on the skin

lightheadedness or dizziness

lower back or side pain

mental depression

muscle cramps


painful or difficult urination

pounding heartbeat

psychotic reaction

rectal bleeding

seeing, hearing, or feeling things that are not there

severe headache

severe liver reactions

severe stomach pain, cramping, or burning

skin rash

sore throat

sores, ulcers, or white spots on the lips or in the mouth

stiff neck or back

sudden decrease in the amount of urine

swelling or tenderness in the upper stomach

swelling of the face, fingers, feet, or lower legs

troubled breathing, tightness in the chest

unusual bleeding or bruising

unusual tiredness or weakness

vomiting of material that looks like coffee grounds

yellow eyes or skin


Changes in facial skin color

fast or irregular breathing

puffiness or swelling of the eyelids or around the eyes

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose



slow heartbeat

stomach pain

trembling or shaking

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common


Less common

Abnormal vision


change in sense of taste

decreased appetite

decrease in sexual ability

dry mouth

irritability or nervousness

loss of hair

muscle pain

tingling, burning, or prickling sensations

trouble with swallowing

vaginal bleeding

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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