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Aloxi

Palonosetron Hydrochloride

PALONOSETRON is used to prevent nausea and vomiting caused by chemotherapy. It also helps prevent delayed nausea and vomiting that may occur a few days after your treatment. Compare serotonin antagonists.
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Aloxi Side Effects

What should I watch for?

Your condition will be monitored carefully while you are receiving this medicine.

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Interactions with Medications

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Less common

Blurred vision

chest pain or discomfort

confusion

difficult breathing

dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly

fainting

fever

irregular heartbeats that continue

sweating

unusual tiredness or weakness

Rare

Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site

extra heartbeats

nervousness

pain in the shoulders, arms, jaw, or neck

pounding in the ears

slow or fast heartbeat

Incidence not known

Agitation

diarrhea

overactive reflexes

poor coordination

restlessness

shivering

talking or acting with excitement you cannot control

trembling or shaking

twitching

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Bluish color of the fingernails, lips, skin, palms, or nail beds

collapse

gasping to breathe

paleness of the skin

seizures

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Difficulty having a bowel movement (stool)

headache

Less common

Acid or sour stomach

belching

bloated or full feeling

blood in the urine

bloody or black, tarry stools

burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

change in vision

chills

continuing ringing or buzzing

cough

decrease in frequency of urination

decrease in urine volume

deep breathing

difficulty in passing urine

drowsiness

dry mouth

excess air or gas in the stomach or intestines

excessive sleeping

eye irritation

fear

feeling happy

feeling of warmth

flushed dry skin

fruit-like breath odor

general feeling of discomfort or illness

hearing loss

heartburn

hiccups

impaired vision

increased hunger

increased thirst

increased urination

indigestion

joint pain

large, flat, blue or purplish patches in the skin

loss of appetite

muscle aches and pains

muscle tremors

numbness or tingling in the hands, feet, or lips

painful knees and ankles

painful urination

passing gas

raised red swellings on the skin, the buttocks, legs or ankles

rash

red, sore eyes

redness of the face, neck, arms, and occasionally, upper chest

runny nose

sore throat

stomach discomfort, upset, or pain

sugar in the urine

swelling or protruding veins

trouble sleeping

unexplained noise in the ears

unexplained weight loss

unusually deep sleep

unusually long duration of sleep

vein discoloration

weakness or heaviness of the legs

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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