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Aldesleukin
Specialty Drug

Proleukin

ALDESLEUKIN, IL-2 (al des LOO kin) is a chemotherapy drug. It is usually used for advanced renal cell cancer or for advanced melanoma. It is sometimes used for other cancers. Compare lymphocyte growth factors.
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Aldesleukin Side Effects

What should I watch for?

Your condition will be monitored carefully while you are receiving this medicine.

Visit your doctor or health care professional for regular checks on your progress. You will need frequent blood checks.

Try to avoid people who are sick. If you get a cold or other infection while receiving this medicine, call your doctor or health care professional. Do not treat yourself. The medicine may decrease your body's ability to fight infections.

The medicine may make you feel generally unwell. This is not uncommon. Tell your doctor or health care professional about any side effects or problems you develop.

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Interactions with Medications

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

Agitation

confusion

diarrhea

dizziness

drowsiness

fever or chills

mental depression

nausea and vomiting

shortness of breath

sores in the mouth and on lips

tingling of the hands or feet

unusual decrease in urination

unusual tiredness or weakness

weight gain of 5 to 10 pounds or more

Less common

Bloating and stomach pain

blurred or double vision

faintness

fast or irregular heartbeat

loss of taste

rapid breathing

redness, swelling, and soreness of the tongue

trouble with speaking

yellow eyes and skin

Rare

Changes in menstrual periods

clumsiness

coldness

convulsions (seizures)

listlessness

muscle aches

pain or redness at injection site

sudden inability to move

swelling in the front of the neck

swelling of the feet or lower legs

weakness

Less common

Black, tarry stools

blisters on the skin

blood in the urine

bloody vomit

chest pain

cough or hoarseness

lower back or side pain

painful or difficult urination

pinpoint red spots on the skin

stomach pain (severe)

unusual bleeding or bruising

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Dry skin

loss of appetite

skin rash or redness with burning or itching, followed by peeling

unusual feeling of discomfort or illness

Less common

Constipation

headache

joint pain

muscle pain

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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